{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T03:42:02Z","timestamp":1791949322723,"version":"4.3.4"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,8,28]],"date-time":"2018-08-28T00:00:00Z","timestamp":1535414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Despite being a well\u2010recognised cause of allergic contact dermatitis with an embargo in many countries around the world, bufexamac is available over the counter in topical preparations in Australia. We present a series of patients who developed severe cutaneous eruptions after the topical application of bufexamac containing preparations to highlight the potential risks of this medication, as well as advocate for the reconsideration of its registration by the Therapeutic Goods Administration in Australia.<\/jats:p>","DOI":"10.1111\/ajd.12910","type":"journal-article","created":{"date-parts":[[2018,8,30]],"date-time":"2018-08-30T05:25:28Z","timestamp":1535606728000},"page":"53-56","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Severe cutaneous eruptions following the topical use of preparations containing bufexamac: Is it time to reconsider its registration in Australia?"],"prefix":"10.1111","volume":"60","author":[{"given":"Adam G","family":"Harris","sequence":"first","affiliation":[{"name":"Department of Dermatology John Hunter Hospital Newcastle New South Wales Australia"},{"name":"Faculty of Medicine University of Newcastle Newcastle New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3502-6713","authenticated-orcid":false,"given":"Samra L","family":"Saikal","sequence":"additional","affiliation":[{"name":"Department of Dermatology John Hunter Hospital Newcastle New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jim","family":"Scurry","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology John Hunter Hospital Newcastle New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Relic","sequence":"additional","affiliation":[{"name":"Department of Dermatology John Hunter Hospital Newcastle New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosemary L","family":"Nixon","sequence":"additional","affiliation":[{"name":"Occupational Dermatology Research and Education Centre Skin and Cancer Foundation Inc. Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Chee","sequence":"additional","affiliation":[{"name":"Department of Dermatology John Hunter Hospital Newcastle New South Wales Australia"},{"name":"Faculty of Medicine University of Newcastle Newcastle New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,28]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Public Australian Register of Therapeutic Goods summaries of products containing bufexamac. Available from URL:https:\/\/www.tga.gov.au\/. (Accessed 21 October 2018.)"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.2012.00876.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.01883.x"},{"key":"e_1_2_6_5_1","unstructured":"Summary of data on the benefits and risks for bufexamac\u2010containing medicines indicated for the relief of dermatitis rash and hives from the minutes of the 145th Medicines Adverse Reactions Committee Meeting can be found athttp:\/\/www.medsafe.govt.nz(Accessed 21 October 2017.)"},{"key":"e_1_2_6_6_1","unstructured":"Medsafe New Zealand.Summary of data on the benefits and risks for bufexamac\u2010containing medicines indicated for the relief of dermatitis rash and hives from the minutes of the 145th Medicines Adverse Reactions Committee Meeting."},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.12186"},{"key":"e_1_2_6_8_1","unstructured":"Adverse events reports to the Therapeutic Goods Administration associated with products containing bufexamac can be found through The Database of Adverse Events Notifications. Available from URL:https:\/\/www.tga.gov.au\/. (Accessed 21 October 2018.)"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2004.tb00524.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2011.01261.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000251127"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajd.12910","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.12910","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T16:34:27Z","timestamp":1694709267000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.12910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,28]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1111\/ajd.12910"],"URL":"https:\/\/doi.org\/10.1111\/ajd.12910","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,28]]},"assertion":[{"value":"2018-06-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}