{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:21:25Z","timestamp":1740126085894,"version":"3.37.3"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T00:00:00Z","timestamp":1536883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2019,5]]},"abstract":"Abstract<\/jats:title>Background\/Objectives<\/jats:title>The aim of this study was to describe a previously unreported association of oral pemphigus vulgaris<\/jats:styled-content> with short\u2010lived blood\u2010filled painless blisters resembling angina bullosa haemorrhagica (ABH<\/jats:styled-content>).<\/jats:p><\/jats:sec>Methods<\/jats:title>A cross\u2010sectional study of consecutive patients with Pemphigus vulgaris. All patients were examined for the presence of ABH<\/jats:styled-content>\u2010like lesions, and demographic, clinical and histopathological data were collected. Histopathological examination was performed when feasible.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 318 with pemphigus vulgaris were included (63.5% female, mean age: 46\u00a0years). ABH<\/jats:styled-content>\u2010like lesions were present in 82 (25.8%) patients, commonly observed in the buccal mucosa (47, 57.3%) followed by the palate (15, 18.3%). All patients had normal platelet counts with no evidence of bleeding diathesis. Biopsies of the ABH<\/jats:styled-content>\u2010like lesions showed suprabasal clefts in four of six samples. ABH<\/jats:styled-content>\u2010like lesions were significantly associated with partial remission of pemphigus vulgaris (47.5%, P<\/jats:italic>\u00a0=\u00a00.002) and the use of intraoral steroids (P<\/jats:italic>\u00a0=\u00a00.001, odds ratio: 5.9 [95% confidence interval: 2.5\u201313.6]).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>ABH<\/jats:styled-content>\u2010like lesions may represent a transient or abortive form of oral pemphigus vulgaris<\/jats:styled-content> and tend to have a benign and self\u2010limiting nature.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajd.12923","type":"journal-article","created":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T17:03:34Z","timestamp":1536944614000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Angina bullosa haemorrhagica\u2010like lesions in pemphigus vulgaris"],"prefix":"10.1111","volume":"60","author":[{"given":"Kamran","family":"Balighi","sequence":"first","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Razi Dermatology Hospital Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1020-8895","authenticated-orcid":false,"given":"Maryam","family":"Daneshpazhooh","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Razi Dermatology Hospital Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4641-4626","authenticated-orcid":false,"given":"Nessa","family":"Aghazadeh","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Razi Dermatology Hospital Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5146-0395","authenticated-orcid":false,"given":"Ziba","family":"Rahbar","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Razi Dermatology Hospital Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1890-1005","authenticated-orcid":false,"given":"Hamidreza","family":"Mahmoudi","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Razi Dermatology Hospital Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adele","family":"Sadjadi","sequence":"additional","affiliation":[{"name":"Autoimmune Bullous Diseases Research Center Razi Dermatology Hospital Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,14]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_5_2_1","DOI":"10.1111\/j.1365-4632.2004.02501.x"},{"doi-asserted-by":"publisher","key":"e_1_2_5_3_1","DOI":"10.1111\/j.1365-4632.2007.03334.x"},{"key":"e_1_2_5_4_1","first-page":"112","article-title":"Oral manifestations of pemphigus vulgaris: clinical presentation, differential diagnosis and management","volume":"1","author":"Bascones\u2010Martinez A","year":"2009","journal-title":"J. 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