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We present two patients with MC during treatment with idarubicin and all\u2010trans\u2010retinoic acid (ATRA) for acute promyelocytic leukaemia (APL). Anthracyclines can be excreted through sweat and induce MC through exfoliation. The use of idarubicin in combination with ATRA would favour the process of producing a peeling effect. Reports of MC associated with idarubicin and ATRA are scarce. Recognizing this benign entity and its triggers will help to differentiate it from other skin reactions, improving the management of patients by avoiding unnecessary studies and treatments.<\/jats:p>","DOI":"10.1111\/ajd.13641","type":"journal-article","created":{"date-parts":[[2021,6,9]],"date-time":"2021-06-09T15:41:47Z","timestamp":1623253307000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Miliaria crystallina induced by idarubicin and all\u2010trans\u2010retinoic acid: Two case reports"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7925-5433","authenticated-orcid":false,"given":"Sandra","family":"Valenzuela\u2010Ubi\u00f1a","sequence":"first","affiliation":[{"name":"Unidad de Gesti\u00f3n Cl\u00ednica de Dermatolog\u00eda M\u00e9dico\u2010Quiru\u0301rgica y Venereolog\u00eda Hospital Universitario Puerta del Mar C\u00e1diz Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Villegas\u2010Romero","sequence":"additional","affiliation":[{"name":"Unidad de Gesti\u00f3n Cl\u00ednica de Dermatolog\u00eda M\u00e9dico\u2010Quiru\u0301rgica y Venereolog\u00eda Hospital Universitario Puerta del Mar C\u00e1diz Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Jim\u00e9nez\u2010Gallo","sequence":"additional","affiliation":[{"name":"Unidad de Gesti\u00f3n Cl\u00ednica de Dermatolog\u00eda M\u00e9dico\u2010Quiru\u0301rgica y Venereolog\u00eda Hospital Universitario Puerta del Mar C\u00e1diz Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5542-5274","authenticated-orcid":false,"given":"Cintia","family":"Arjona\u2010Aguilera","sequence":"additional","affiliation":[{"name":"Servicio de Dermatolog\u00eda M\u00e9dico\u2010Quiru\u0301rgica y Venereolog\u00eda, Hospital de Poniente El Ejido, Almer\u00eda Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Linares\u2010Barrios","sequence":"additional","affiliation":[{"name":"Unidad de Gesti\u00f3n Cl\u00ednica de Dermatolog\u00eda M\u00e9dico\u2010Quiru\u0301rgica y Venereolog\u00eda Hospital Universitario Puerta del Mar C\u00e1diz Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,6,9]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2016.2816"},{"key":"e_1_2_4_3_1","first-page":"275","article-title":"Rare skin disorder complicating doxorubicin therapy: miliaria crystallina","volume":"12","author":"Godkar D","year":"2005","journal-title":"Am. 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