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We report a case of a woman treated successfully for psoriasis and psoriatic arthritis with the IL\u201017 inhibitor secukinumab whilst simultaneously being treated for severe asthma and nasal polyps, initially with the IL\u20105 inhibitor benralizumab, followed by dupilumab, a monoclonal antibody that targets the IL\u20104 receptor alpha subunit which blocks signalling from both IL\u20104 and IL\u201013.<\/jats:p>","DOI":"10.1111\/ajd.13676","type":"journal-article","created":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T19:06:04Z","timestamp":1628535964000},"page":"506-508","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Combination treatment with monoclonal antibodies: Secukinumab, benralizumab and dupilumab for the combined management of psoriasis and severe asthma"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9976-2691","authenticated-orcid":false,"given":"Patrick D","family":"Mahar","sequence":"first","affiliation":[{"name":"Skin Health Institute Inc Melbourne Victoria Australia"},{"name":"Royal Children\u2019s Hospital Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celia M","family":"Zubrinich","sequence":"additional","affiliation":[{"name":"Alfred Health Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick","family":"Manuelpillai","sequence":"additional","affiliation":[{"name":"Skin Health Institute Inc Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Foley","sequence":"additional","affiliation":[{"name":"Skin Health Institute Inc Melbourne Victoria Australia"},{"name":"St Vincent\u2019s Hospital Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,8,9]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.11.057"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201810-1944CI"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21051690"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00341-2020"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/1759720X16665330"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.120924"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.20221"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-242211"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40272-020-00396-1"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2019.1659481"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaa568"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.13676","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ajd.13676","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.13676","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T18:00:25Z","timestamp":1692813625000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.13676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,9]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1111\/ajd.13676"],"URL":"https:\/\/doi.org\/10.1111\/ajd.13676","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,9]]},"assertion":[{"value":"2021-06-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}