{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:48:55Z","timestamp":1778618935828,"version":"3.51.4"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T00:00:00Z","timestamp":1629072000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Subcutaneous panniculitis\u2010like T\u2010cell lymphoma (SPTCL) is a rare cytotoxic T\u2010cell lymphoma preferentially involving subcutis. A link between patients with SPTCL and <jats:italic>HAVCR2<\/jats:italic> mutations has recently been discovered. We present a 14\u2010year\u2010old girl of Chinese heritage who was diagnosed with SPTCL in the context of homozygous <jats:italic>HAVCR2<\/jats:italic> status for c.245A&gt;G p. (Tyr82Cys) and achieved complete remission after treatment with cyclosporin and steroids. Dermatologists should be aware of the diagnostic, management and familial genetic counselling utility of <jats:italic>HAVCR2<\/jats:italic> for investigating and managing patients with SPTCL.<\/jats:p>","DOI":"10.1111\/ajd.13684","type":"journal-article","created":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T12:45:26Z","timestamp":1629117926000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Subcutaneous panniculitis\u2010like T\u2010cell lymphoma in a 14\u2010year\u2010old female homozygous for <i>HAVCR2<\/i> mutation"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6768-4687","authenticated-orcid":false,"given":"Aaron J","family":"Frederiks","sequence":"first","affiliation":[{"name":"Department of Dermatology Perth Children\u2019s Hospital Nedlands Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominic V","family":"Spagnolo","sequence":"additional","affiliation":[{"name":"PathWest Laboratory Medicine Nedlands Australia"},{"name":"Division of Pathology and Laboratory Medicine School of Medicine University of Western Australia Nedlands Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shanti","family":"Ramachandran","sequence":"additional","affiliation":[{"name":"Department of Oncology, Haematology, Blood and Marrow Transplantation Perth Children\u2019s Hospital Nedlands Australia"},{"name":"School of Paediatrics and Child Health University of Western Australia Nedlands Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Brand","sequence":"additional","affiliation":[{"name":"Department of Dermatology Perth Children\u2019s Hospital Nedlands Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,8,16]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"383","volume-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues","author":"Jaffe E","year":"2017"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-04-087288"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2543"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.05.1243"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0251-4"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2018028340"},{"key":"e_1_2_7_8_1","first-page":"1058","article-title":"HAVCR2 mutations are associated with severe hemophagocytic syndrome in subcutaneous panniculitis\u2010like T\u2010cell lymphoma","volume":"135","author":"Sonigo G","year":"2020","journal-title":"Blood"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0000000000001954"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24462"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2018.00198"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546630305542"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.13684","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ajd.13684","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.13684","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T18:00:16Z","timestamp":1692813616000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.13684"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,16]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1111\/ajd.13684"],"URL":"https:\/\/doi.org\/10.1111\/ajd.13684","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,16]]},"assertion":[{"value":"2021-03-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}