{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:35:33Z","timestamp":1747182933319,"version":"3.40.5"},"reference-count":8,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T00:00:00Z","timestamp":1632700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2021,11]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Crusted scabies results from a failure of the host immune response to control the proliferation of the scabies mite in the skin, with resulting hyperinfestation and a concomitant inflammatory and hyper\u2010keratotic reaction. However, it has also been recognised in people with no evident immunological deficit.<\/jats:p><\/jats:sec>Case history<\/jats:title>We present a case report of apparently immunocompetent 16\u2010year\u2010old female presenting with multiple hyperkeratotic vegetating plaques over limbs, excoriated papules over trunk with minimal itching since 2\u2009years without any positive family history. The microscopic examination of the skin scales with potassium hydroxide demonstrated numerous scabies mites and eggs. Histopathology showed hyperkeratosis with multiple mites in stratum corneum. Numerous mites were seen on biopsy of lesion. X\u2010ray showed osteolysis of distal phalanges secondary to chronic pressure. Repeated topical treatments with permethrin and oral ivermectin led to the considerable resolution of her lesions.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>We present a rare case of crusted scabies with osteolysis in an immunocompetent female.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajd.13726","type":"journal-article","created":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T19:55:51Z","timestamp":1632772551000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unusual presentation of crusted scabies with osteolysis in immunocompetent"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6136-1278","authenticated-orcid":false,"given":"Sunanda Arun","family":"Mahajan","sequence":"first","affiliation":[{"name":"Department of Dermatology Seth G.S. Medical College and K.E.M Hospital Parel, Mumbai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aditi","family":"Chhonkar","sequence":"additional","affiliation":[{"name":"Department of Dermatology Seth G.S. Medical College and K.E.M Hospital Parel, Mumbai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2477-5356","authenticated-orcid":false,"given":"Jayati Shailesh","family":"Dave","sequence":"additional","affiliation":[{"name":"Department of Dermatology Seth G.S. Medical College and K.E.M Hospital Parel, Mumbai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naziya","family":"Muhammed","sequence":"additional","affiliation":[{"name":"Department of Dermatology Seth G.S. Medical College and K.E.M Hospital Parel, Mumbai India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,27]]},"reference":[{"volume-title":"Treatment of Leprosy or Greek Elephantiasis","year":"1848","author":"Danielsen DG","key":"e_1_2_7_2_1"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.79.932.341"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2004.08.033"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1201-9712(98)90118-7"},{"key":"e_1_2_7_6_1","first-page":"565","article-title":"Histocompatibility (HLA) antigens in Egyptians with two parasitic skin diseases (scabies and leishmaniasis)","volume":"20","author":"Morsy TA","year":"1990","journal-title":"J. Egypt Soc. 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