{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T02:12:57Z","timestamp":1790475177688,"version":"4.1.0"},"reference-count":8,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T00:00:00Z","timestamp":1637712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Calciphylaxis is a potencially disorder in patients with hyperphosphatemic familial tumoral calcinosis (HFTC). Patients commonly present livedo racemosa and retiform purpura, which may progress to necrosis and very painful ulcers. Treatment with sodium thiosulfate provides good results; however, intralesional and intravenous treatment can be limited by its adverse effects. Topical sodium thiosulfate has been successfully reported for cutaneous calcification associated with connective tissue diseases and calciphylaxis in patients with chronic kidney disease. We provide a case report of a patient with HFTC and calciphylaxis who was treated with topical sodium thiosulfate with a rapid and complete response with no side effects.<\/jats:p>","DOI":"10.1111\/ajd.13750","type":"journal-article","created":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T10:44:03Z","timestamp":1637750643000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Therapeutic success of sodium thiosulfate in treating cutaneous calciphylaxis in a patient with hyperphosphataemic familial tumoral calcinosis"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1558-657X","authenticated-orcid":false,"given":"Sheila","family":"Requena","sequence":"first","affiliation":[{"name":"Departament of Dermatology Hospital Universitario Central de Asturias Oviedo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Santos\u2010Juanes","sequence":"additional","affiliation":[{"name":"Departament of Dermatology Hospital Universitario Central de Asturias Oviedo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Morales","sequence":"additional","affiliation":[{"name":"Department of Pathological Anatomy Hospital Universitario Central de Asturias Oviedo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"G\u00f3mez","sequence":"additional","affiliation":[{"name":"Departament of Metabolism Hospital Universitario Central de Asturias Oviedo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,24]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2015.09.001"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.09880912"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-139X.2010.00738.x"},{"key":"e_1_2_4_5_1","first-page":"9","article-title":"Calcinosis cut\u00e1nea grave tratada exitosamente con una f\u00f3rmula magistral t\u00f3pica W\/O de tiosulfato s\u00f3dico al 10%","volume":"72","author":"P\u00e9rez\u2010Moreno MA","year":"2014","journal-title":"Acta. 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