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Therefore, diagnosis can often be challenging, requiring a thorough dermatological examination along with distinctive histological and immunopathological characteristics. Lichenoid degeneration of the basal epidermis exposes various antigens of the dermal\u2013epidermal junction in LPP, resulting in the breakdown of immune tolerance, hence, the production of autoantibodies against type XVII collagen. Conversely, no pathogenic autoantibodies are detected in BLP. However, some cases of mucosal lichen planus might display immunopathological features suggestive of autoimmune blistering diseases. Therefore, a better understanding of the pathophysiology of these two distinct dermatoses is imperative. The aim of this review was to provide a summary of the current knowledge on the clinical hallmarks, diagnosis and available therapeutic options in LPP and BLP.<\/jats:p>","DOI":"10.1111\/ajd.13808","type":"journal-article","created":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T17:59:03Z","timestamp":1645639143000},"page":"165-171","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Challenges and pitfalls between lichen planus pemphigoides and bullous lichen planus"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7315-4711","authenticated-orcid":false,"given":"Cristian","family":"Papara","sequence":"first","affiliation":[{"name":"Department of Dermatology Iuliu Hatieganu University of Medicine and Pharmacy  Cluj\u2010Napoca 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