{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T20:04:59Z","timestamp":1748549099861,"version":"3.40.5"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T00:00:00Z","timestamp":1651449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Bullous pemphigoid is a common autoimmune blistering skin disease that is significantly associated with a high rate of morbidity and mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>Our aim was to determine the 1\u2010, 2\u2010 and 3\u2010year mortality rate and standardized mortality ratio of BP in Moroccan patients, as well as to identify risk factors that influence survival both in the 1st and 3rd year of follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients with BP diagnosed between January 2008 and December 2017 in a tertiary referral centre at the Mohammed V Military Hospital in Morocco were included retrospectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 1\u2010year, 2\u2010year and 3\u2010year mortality rates of the cases were 25.8%, 32.3% and 43%, respectively. The median age of onset was 72\u2009years (range, 64\u2009\u223c\u200980\u2009years), and 51 (54.8%) patients were men. The standardized mortality ratio of patients with BP was 2.6 times higher than that of age\u2010 and sex\u2010matched members of the general Moroccan population. Besides advanced age, the presence of diabetes mellitus at the time of diagnosis was associated with increased 3\u2010year mortality in multivariate analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This is the first study analysing the mortality rate of bullous pemphigoid in Morocco. Our findings confirm a high mortality rate for BP patients compared with the expected mortality rate for age\u2010 and sex\u2010adjusted general Moroccan population. Risk factors for increased 3\u2010year mortality include advanced age at the time of diagnosis and diabetes mellitus.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajd.13852","type":"journal-article","created":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T19:18:37Z","timestamp":1651519117000},"page":"328-334","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Mortality and prognostic factors of Bullous Pemphigoid in a Moroccan population"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9290-7627","authenticated-orcid":false,"given":"Hicham","family":"Titou","sequence":"first","affiliation":[{"name":"Department of Dermatology\u2010Venereology, Mohammed V Military Teaching Hospital Mohammed V University in Rabat  Rabat Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoufal","family":"Hjira","sequence":"additional","affiliation":[{"name":"Department of 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