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We report a case of a 31\u2010year\u2010old man presented with skin atrophy, purpura and milia on the hips and shoulders after taking penicillamine for 1.5 years. According to literature review, this type of penicillamine\u2010associated cutaneous adverse effect belongs to degenerative dermopathy, which mostly occurs on bony prominences and points of pressure in patients with Wilson's disease or cystinuria. Withdrawal or reduction of drug dose can improve the features of degenerative dermopathy.<\/jats:p>","DOI":"10.1111\/ajd.13963","type":"journal-article","created":{"date-parts":[[2022,12,24]],"date-time":"2022-12-24T11:44:15Z","timestamp":1671882255000},"page":"126-130","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Penicillamine\u2010induced degenerative dermopathy in a patient with Wilson's disease"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3845-1176","authenticated-orcid":false,"given":"Yuting","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Dermatology, Zhongshan Hospital (Xiamen branch) Fudan University Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yangyang","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Zhongshan Hospital (Xiamen branch) Fudan University Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meiqing","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Zhongshan Hospital (Xiamen branch) Fudan University Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Zhongshan Hospital (Xiamen branch) Fudan University Xiamen China"},{"name":"Department of Dermatology, Zhongshan Hospital Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyan","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Zhongshan Hospital (Xiamen branch) Fudan University Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9918-1021","authenticated-orcid":false,"given":"Lujuan","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Zhongshan Hospital (Xiamen branch) Fudan University Xiamen China"},{"name":"Department of Dermatology, Zhongshan Hospital Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,12,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257\u2010013\u20100022\u2010z"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.5114\/ninp.2013.34397"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0190\u20109622(83)70062\u20109"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23031824"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10237\u2010019\u201001187\u20105"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019\u20105154.160498"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13153"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.5070\/D3225030951"},{"issue":"5","key":"e_1_2_6_10_1","doi-asserted-by":"crossref","first-page":"703","DOI":"10.47102\/annals-acadmedsg.V32N5p703","article-title":"A case of penicillamine\u2010induced dermopathy","volume":"32","author":"Tang MB","year":"2003","journal-title":"Ann Acad Med Singapore"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102230.1987.tb01862.x"},{"key":"e_1_2_6_12_1","unstructured":"International drug monitoring: the role of national centres. 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