{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T17:42:30Z","timestamp":1784569350243,"version":"3.55.0"},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T00:00:00Z","timestamp":1683504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Chronic hand and foot eczema (CHFE) is a common inflammatory disorder that generally lasts for over 3\u2009months. If it is intractable to topical agents, systemic immunomodulators can be considered; however, they are not suitable for long\u2010term management because of their adverse effects. Baricitinib is an oral Janus kinase inhibitor that has been approved for the treatment of moderate\u2010to\u2010severe atopic dermatitis. However, its effect on CHFE has rarely been described. Herein, we report nine cases of recalcitrant CHFE that were treated with baricitinib after an inadequate response to low\u2010dose ciclosporin. All patients had more than moderate improvement within 2\u20138\u2009weeks without serious adverse effects.<\/jats:p>","DOI":"10.1111\/ajd.14074","type":"journal-article","created":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T10:52:07Z","timestamp":1683543127000},"page":"408-412","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Nine cases of chronic hand and foot eczema treated with baricitinib"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5750-4558","authenticated-orcid":false,"given":"Sang\u2010Doo","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Dermatology, Kyung Hee University College of Medicine Kyung Hee University Hospital  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0085-9566","authenticated-orcid":false,"given":"Hye\u2010Jin","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Kyung Hee University College of Medicine Kyung Hee University Hospital  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9834-7931","authenticated-orcid":false,"given":"Min Kyung","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Kyung Hee University College of Medicine Kyung Hee University Hospital  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12370"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.5414\/ALX02272E"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06270.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14039"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12840"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700781"},{"key":"e_1_2_7_8_1","unstructured":"SimpsonEL RahawiK HuX BlauveltA PappKA ChuCY et al.Effect of upadacitinib on hand eczema in patients with moderate\u2010to\u2010severe atopic dermatitis: results from two phase 3 trials (measure up 1 and measure up 2). Poster presented at: 30th EADV Virtual Congress; October 29 2021."},{"key":"e_1_2_7_9_1","unstructured":"Asana BioSciences.A phase 2b randomized double\u2010blind placebo\u2010controlled study to evaluate the efficacy safety tolerability and pharmacokinetics of gusacitinib (ASN002) in subjects with moderate\u2010to\u2010severe chronic hand eczema. Presented at EADV Virtual Congress.2020."},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16948"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2020.3260"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.14074","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T01:07:23Z","timestamp":1697072843000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.14074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,8]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1111\/ajd.14074"],"URL":"https:\/\/doi.org\/10.1111\/ajd.14074","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,8]]},"assertion":[{"value":"2022-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}