{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T21:24:14Z","timestamp":1784064254580,"version":"3.55.0"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,7,6]],"date-time":"2023-07-06T00:00:00Z","timestamp":1688601600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000948","name":"Pfizer Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000948","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Alopecia areata (AA) is a common immune\u2010mediated non\u2010scarring hair loss, with a worldwide incidence between 0.57% and 3.8%. The incidence and prevalence of AA in the Australian general population have not been previously reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the incidence and prevalence of AA in Australia using primary care data. A secondary objective was to identify common demographic characteristics, comorbidities and treatment patterns among Australians living with AA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analysed electronic health record data captured from a national clinical practice management software over a 10\u2010year index period between 2011 and 2020 calendar years, inclusive. The incidence of new\u2010onset AA and the prevalence of active records with AA were estimated. Differences in incidence by sociodemographic groups, and patterns of treatment were also evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 976 incident AA records. The incidence of new\u2010onset AA in the total study cohort was 0.278 per 1000 person\u2010years (95% CI 0.26\u20130.295). By age, the incidence was highest in the 19\u2010 to 34\u2010year\u2010old age bracket (0.503 per 1000 person\u2010years: 95% CI 0.453\u20130.554). AA incidence was lower among females than males (IRR 0.763, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, 95% CI 0.673\u20130.865). Among active records, 520 were prevalent AA records. AA point prevalence at 31\/12\/2020 was 0.13% (1.26 per 1000 persons; 95% CI 1.15\u20131.37).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This is the first study to describe the epidemiology (incidence and point prevalence) and management of AA in the Australian primary health\u2010care population through large\u2010scale database analysis. Incidence and prevalence findings were consistent with earlier estimates from other regions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajd.14126","type":"journal-article","created":{"date-parts":[[2023,7,6]],"date-time":"2023-07-06T07:52:44Z","timestamp":1688629964000},"page":"330-338","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Incidence and prevalence of alopecia areata in the Australian primary care setting: A retrospective analysis of electronic health record data"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6751-1428","authenticated-orcid":false,"given":"R.","family":"Sinclair","sequence":"first","affiliation":[{"name":"University of Melbourne  Melbourne Victoria Australia"},{"name":"Epworth HealthCare  East Melbourne Victoria Australia"},{"name":"Sinclair Dermatology  East Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Eisman","sequence":"additional","affiliation":[{"name":"Sinclair Dermatology  East Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Song","sequence":"additional","affiliation":[{"name":"Prospection Pty Ltd  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Heung","sequence":"additional","affiliation":[{"name":"MedicalDirector Clinical  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Surian","sequence":"additional","affiliation":[{"name":"Pfizer  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. M. Y.","family":"Lee","sequence":"additional","affiliation":[{"name":"Pfizer  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Witcombe","sequence":"additional","affiliation":[{"name":"Pfizer  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,6]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2014.10.014"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.874677"},{"key":"e_1_2_10_4_1","first-page":"397","article-title":"Epidemiology and burden of alopecia areata: a systematic review","volume":"8","author":"Villasante Fricke AC","year":"2015","journal-title":"Clin, Cosmet Investig Dermatol"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.3049"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.07.013"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-015468"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.07.044"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.464"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.20628"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S245649"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.16615"},{"key":"e_1_2_10_13_1","unstructured":"World Health Organization.ICD\u201010: International Statistical Classification of Diseases and Related Health Problems\/World Health Organization. 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Accessed January10 2023.https:\/\/www.abs.gov.au\/statistics\/health\/mental\u2010health\/patterns\u2010use\u2010mental\u2010health\u2010services\u2010and\u2010prescription\u2010medications\/latest\u2010release2011."}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.14126","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T01:06:32Z","timestamp":1697072792000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.14126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,6]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1111\/ajd.14126"],"URL":"https:\/\/doi.org\/10.1111\/ajd.14126","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,6]]},"assertion":[{"value":"2023-03-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}