{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:43:29Z","timestamp":1787013809421,"version":"build-2736575974"},"reference-count":64,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T00:00:00Z","timestamp":1690502400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008897","name":"Janssen Pharmaceuticals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008897","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Over the last decade, the treatment landscape for moderate\u2013severe psoriasis has rapidly evolved. The Australasian College of Dermatologists sought to review and update previously published treatment goals for moderate\u2013severe psoriasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A modified Delphi approach was used. Comprehensive literature review and guideline evaluation resulted in the development of statements and other questions to establish current clinical practices. Two rounds of anonymous voting were undertaken, with a collaborative meeting held in between to discuss areas of discordance. Overall, consensus was defined as achievement of \u226575% agreement in the range 7\u20139 on a 9\u2010point scale (1 strongly disagree; 9 strongly agree).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Consensus was achieved on 26\/29 statements in round 1 and a further 20 statements in round 2. There was strong agreement to expanding the classification\/definition of psoriasis severity by including a choice of metrics, incorporating quality of life measures, and widening the scope of high\u2010impact sites. Consensus was also reached on revised treatment response criteria, which were then incorporated into a new treatment algorithm. There was discordance with the current requirement to undertake a trial with established systemic agents before accessing targeted therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The ability of new targeted treatment options to change the narrative in psoriasis patient care can only be properly realised if challenges to timely and equitable access are addressed. The proposed framework for the assessment, classification and management of moderate\u2013severe psoriasis aligns with international recommendations. Its adoption into Australian clinical practice is hoped to improve treatment outcomes and patients' satisfaction with their care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ajd.14138","type":"journal-article","created":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T03:46:27Z","timestamp":1690515987000},"page":"476-487","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Australian consensus: Treatment goals for moderate to severe psoriasis in the era of targeted therapies \u2013 Adult patients"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5891-5607","authenticated-orcid":false,"given":"Peter","family":"Foley","sequence":"first","affiliation":[{"name":"Skin Health Institute  Carlton Victoria Australia"},{"name":"Department of Dermatology St Vincent's Hospital Melbourne  Fitzroy Victoria Australia"},{"name":"The University of Melbourne  Melbourne Victoria 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