{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T02:41:19Z","timestamp":1785552079782,"version":"3.56.0"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T00:00:00Z","timestamp":1694995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2022NSFC0713"],"award-info":[{"award-number":["2022NSFC0713"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hand\u2010held dermoscopy is a valuable tool for dermatologists, but it has been rarely used to assess the nail fold capillary (NFC) in patients with dermatomyositis (DM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients were collected from the Department of Dermatology and Venereology from July 2020 to July 2021, and the follow\u2010up was conducted until January 2022. Demographic features, disease activity and NFC changes were analysed using a hand\u2010held dermoscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The most common NFC finding in our study was bushy capillary (87.0%). There was no significant improvement in scleroderma\u2013dermatomyositis (SD)\u2010like nail fold changes or enlarged capillaries from baseline to 12\u2009weeks of treatment (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05) or from 12\u2009weeks to 24\u2009weeks of treatment (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05), but there was a significant improvement from baseline to 24\u2009weeks of treatment (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The avascular area did not improve from baseline to 12\u2009weeks of follow\u2010up, but the changes were significant from 12\u2009weeks to 24\u2009weeks of treatment (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) and baseline to 24\u2009weeks of treatment (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Periungual erythema improved significantly from baseline to 12\u2009weeks of treatment (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) and baseline to 24\u2009weeks of treatment (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05), but it did not improve significantly from 12\u2009weeks to 24\u2009weeks of treatment (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). There was no significant difference in disease activity between patients with or without specific NFC changes. However, some NFC features improved as disease activity decreased.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Dermoscopy of NFC is a cost\u2010effective option for the preliminary diagnosis of DM. Further, long\u2010term follow\u2010up is necessary to study the relationship between disease activity and NFC changes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajd.14157","type":"journal-article","created":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T06:18:58Z","timestamp":1695104338000},"page":"514-521","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Assessment of nail fold capillary changes by hand\u2010held dermoscopy in adult dermatomyositis: A single\u2010centre prospective study"],"prefix":"10.1111","volume":"64","author":[{"given":"Aliza","family":"Paudyal","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology, West China Hospital Sichuan University  Chengdu China"},{"name":"Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease\u2010Related Molecular Network West China Hospital, Sichuan University  Chengdu China"},{"name":"Department of Dermatology and Venereology B.P. Koirala Institute of Health Sciences  Dharan Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7161-6089","authenticated-orcid":false,"given":"Yao","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, West China Hospital Sichuan University  Chengdu China"},{"name":"Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease\u2010Related Molecular Network West China Hospital, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, West China Hospital Sichuan University  Chengdu China"},{"name":"Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease\u2010Related Molecular Network West China Hospital, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8241-2938","authenticated-orcid":false,"given":"Xingwei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, West China Hospital Sichuan University  Chengdu China"},{"name":"Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease\u2010Related Molecular Network West China Hospital, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, West China Hospital Sichuan University  Chengdu China"},{"name":"Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease\u2010Related Molecular Network West China Hospital, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirui","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, West China Hospital Sichuan University  Chengdu China"},{"name":"Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease\u2010Related Molecular Network West China Hospital, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parbatraj","family":"Regmi","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, West China Hospital Sichuan University  Chengdu China"},{"name":"Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease\u2010Related Molecular Network West China Hospital, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Lyu","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, West China Hospital Sichuan University  Chengdu China"},{"name":"Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease\u2010Related Molecular Network West China Hospital, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,18]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(99)05157\u20100"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2003.281"},{"issue":"3","key":"e_1_2_10_4_1","first-page":"270","article-title":"Dermoscopy of pigmented skin lesions","volume":"11","author":"Soyer HP","year":"2001","journal-title":"Eur J Dermatol"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keq430"},{"issue":"8","key":"e_1_2_10_6_1","first-page":"1644","article-title":"Skin involvement in juvenile dermatomyositis is associated with loss of end row nailfold capillary loops","volume":"31","author":"Smith RL","year":"2004","journal-title":"J Rheumatol"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.8.1027"},{"issue":"3","key":"e_1_2_10_8_1","first-page":"539","article-title":"A portable digital microphotography unit for rapid documentation of periungual nailfold capillary changes in autoimmune connective tissue diseases","volume":"31","author":"Sontheimer RD","year":"2004","journal-title":"J Rheumatol"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197502132920706"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0733\u20108635(02)00021\u20109"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(07)61602\u2010X"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780240907"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067\u2010019\u201004537\u2010x"},{"issue":"1","key":"e_1_2_10_14_1","first-page":"71","article-title":"The nail apparatus in collagen disorders","volume":"10","author":"Tosti A","year":"1991","journal-title":"Semin Dermatol"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2017.06.001"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102133.2007.07819.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067\u2010006\u20100489\u20106"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02230332"},{"key":"e_1_2_10_19_1","first-page":"233","article-title":"Association of nailfold capillary changes with disease activity, clinical and laboratory findings in patients with dermatomyositis","volume":"29","author":"Shenavandeh S","year":"2015","journal-title":"Med J Islam Repub Iran"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.683900"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1974.01630120016003"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468\u20103083.2004.00990.x"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067\u2010014\u20102795\u20108"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2008.09.003"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2005.01.001"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.56.7.435"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1159\/000089015"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.25259\/IJDVL_802_19"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keq407"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.14157","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T08:24:04Z","timestamp":1699518244000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.14157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,18]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1111\/ajd.14157"],"URL":"https:\/\/doi.org\/10.1111\/ajd.14157","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,18]]},"assertion":[{"value":"2022-12-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}