{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:36:23Z","timestamp":1790127383239,"version":"4.0.1"},"reference-count":6,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T00:00:00Z","timestamp":1721779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The term \u2018hyperkeratotic flexural erythema\u2019 (HFE) has been used synonymously with granular parakeratosis (GP), to describe a scaly, typically intertriginous rash associated with contact factors such as benzalkonium chloride. However, clinical HFE can occur without the classical GP histological pattern. We reviewed skin biopsies from 10 patients with clinically diagnosed HFE. A progression of histopathological features is suggested. The absence of histological GP should not exclude the clinical diagnosis of HFE when there is a high index of suspicion.<\/jats:p>","DOI":"10.1111\/ajd.14349","type":"journal-article","created":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T12:59:17Z","timestamp":1721825957000},"page":"647-649","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Histological diversity in hyperkeratotic flexural erythema\u2014Beyond granular parakeratosis?"],"prefix":"10.1111","volume":"65","author":[{"given":"Anna","family":"Luo","sequence":"first","affiliation":[{"name":"Department of Dermatology Greenlane Clinical Centre, Te Whatu Ora  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fergus","family":"Oliver","sequence":"additional","affiliation":[{"name":"Department of Dermatology Greenlane Clinical Centre, Te Whatu Ora  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4501-2211","authenticated-orcid":false,"given":"Harriet","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Department of Dermatology Greenlane Clinical Centre, Te Whatu Ora  Auckland New Zealand"},{"name":"Faculty of Medical and Health Sciences University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190\u20109622(91)70078\u2010g"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.16107"},{"issue":"1534","key":"e_1_2_7_4_1","first-page":"128","article-title":"Granular parakeratosis secondary to benzalkonium chloride exposure from common household laundry rinse aids","volume":"134","author":"Tian CJ","year":"2021","journal-title":"N Z Med J"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610\u20100387.2008.06964.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2004.12.031"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257\u2010015\u20100154\u20104"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.14349","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T12:23:56Z","timestamp":1736771036000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.14349"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,24]]},"references-count":6,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1111\/ajd.14349"],"URL":"https:\/\/doi.org\/10.1111\/ajd.14349","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,24]]},"assertion":[{"value":"2024-06-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}