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Rarely, antibodies directed against human epidermal growth factor receptor 2 (HER\u20102), such as trastuzumab, may trigger dermatomyositis, and immune checkpoint inhibitors may incite the Wong variant of dermatomyositis, characterised by clinical and histopathologic features of pityriasis rubra pilaris, including monomorphic keratotic papules. We present an unusual case of dermatomyositis with features of the Wong variant occurring in a 51\u2010year\u2010old female with a history of breast cancer after completion of adjuvant therapy with trastuzumab.<\/jats:p>","DOI":"10.1111\/ajd.14456","type":"journal-article","created":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T03:48:57Z","timestamp":1743997737000},"page":"183-185","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Case Report of Dermatomyositis With Features of the Wong Variant Developing Post\u2010Trastuzumab Therapy for Breast Cancer"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3625-4566","authenticated-orcid":false,"given":"Lauren C.","family":"LaMonica","sequence":"first","affiliation":[{"name":"University of Michigan Medical School  Ann Arbor Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2761-8065","authenticated-orcid":false,"given":"Margaret E.","family":"Lang Houser","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Michigan  Ann Arbor Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0802-2883","authenticated-orcid":false,"given":"Paul W.","family":"Harms","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Michigan  Ann Arbor Michigan USA"},{"name":"Department of Pathology University of Michigan  Ann Arbor Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1048-4462","authenticated-orcid":false,"given":"Frank","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Michigan  Ann Arbor Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,6]]},"reference":[{"key":"e_1_2_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000371573"},{"key":"e_1_2_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000517819"},{"key":"e_1_2_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2018.08.006"},{"key":"e_1_2_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.2147\/JIR.S469401"},{"key":"e_1_2_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.05.034"},{"key":"e_1_2_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416\u2010018\u20100318\u20100"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.14456","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T05:26:48Z","timestamp":1746768408000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.14456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,6]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1111\/ajd.14456"],"URL":"https:\/\/doi.org\/10.1111\/ajd.14456","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,6]]},"assertion":[{"value":"2024-08-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}