{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T09:38:14Z","timestamp":1787737094025,"version":"build-2784847793"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background\/Objectives<\/jats:title><jats:p>To explore the clinical presentation, management and impact on quality of life in women with vulval psoriasis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective, single\u2010centre cohort study of women was conducted at a large dermatology practice from January 2016 to January 2024. Sequential Vulval Quality of Life Index scores and patient data were systematically collected and recorded in an online patient database. Treatment regimens were individualised and titrated to clinical response.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study included a total of 350 patients with vulval psoriasis over an eight\u2010year period. 13.1% of patients required systemic treatment solely for vulval disease. The median VQLI score improved from 18.0\u2009\u00b1\u20099.4 at baseline to 9.7\u2009\u00b1\u20097.6 at the end of follow\u2010up (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). All domains showed statistically significant improvements except for \u2018Sexual Function\u2019. The domains with the greatest improvement were \u2018Future Health Concerns\u2019 (69.2%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), \u2018Feelings and Emotions\u2019 (63.4%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) \u2018Symptoms\u2019 (58.6%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and \u2018Activities of Daily Living\u2019 (56.8%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Relevance<\/jats:title><jats:p>Vulval psoriasis has a substantial impact on quality of life but remains underdiagnosed and undertreated. While treatment can significantly improve outcomes, issues related to sexual function and relationships often persist. Systemic therapy may be required for a subset of patients with vulval\u2010only disease. Routine assessment and targeted management of vulval involvement are crucial to optimising patient well\u2010being.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajd.14492","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T08:19:04Z","timestamp":1745914744000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Adult Vulval Psoriasis: Clinical Presentation, Management and Impact on Quality of Life"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2013-1860","authenticated-orcid":false,"given":"Michelle","family":"Wu","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Health University of Sydney  Camperdown New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gayle","family":"Fischer","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health University of Sydney  Camperdown New South Wales Australia"},{"name":"Department of Dermatology Royal North Shore Hospital  St Leonards New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,29]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m1590"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.02.1127"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555\u2010018\u20100257\u2010y"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102133.2011.10249.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.05.1150"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.10.040"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/000155599750009870"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.13235"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555\u2010017\u20100204\u20103"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000338858"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.2147\/PTT.S169389"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555\u2010021\u201000536\u20106"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555\u2010012\u20100015\u20105"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16736"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.20187"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13110"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/14712598.2023.2236023"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.1402a52"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.13898"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2020.32.3.181"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555\u20101885"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.14492","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T10:13:46Z","timestamp":1754907226000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.14492"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,29]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1111\/ajd.14492"],"URL":"https:\/\/doi.org\/10.1111\/ajd.14492","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,29]]},"assertion":[{"value":"2024-11-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}