{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T20:49:44Z","timestamp":1757623784103,"version":"3.44.0"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T00:00:00Z","timestamp":1749686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","award":["70071713"],"award-info":[{"award-number":["70071713"]}],"id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Atopic dermatitis (AD) significantly impacts quality of life, with well\u2010documented physical and psychological consequences. While disease burden is well characterised, the influence of psychosocial determinants on AD outcomes remains underexplored. This study examines these factors in an Australian paediatric population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate whether children from populations at risk of health inequities\u2014such as those from rural areas, culturally diverse backgrounds, First Nations communities, socioeconomically disadvantaged postcodes, those with neuropsychiatric conditions and \u2018Vulnerable\u2019 children (defined as those under state or relative care or with a history of familial abuse or neglect)\u2014experience more severe disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective cross\u2010sectional study included children \u2264\u200916\u2009years with confirmed AD attending a tertiary paediatric referral centre in Melbourne (Aug 2022\u2014Aug 2023). Risk factors were defined by social determinants of health, including economic, cultural and geographic influences. Disease outcomes (severity, hospitalisations, emergency department visits treatment patterns) were analysed using univariate and multivariate methods. A total of 454 at\u2010risk children were compared to 454 controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Children from at\u2010risk groups were more likely to have severe AD (43.8% vs. 28.3%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), higher annual rates of hospital admissions, increased antibiotic use, and greater prednisolone use for flares (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Multivariate analysis revealed significantly higher odds of severe AD (aMOR 4.72, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and hospitalisation (aIRR 2.73, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) in the at\u2010risk cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Psychosocial determinants of health are associated with increased AD severity and healthcare use in children. These findings highlight the need for targeted, equity\u2010focused interventions to reduce disparities in AD care in Australia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajd.14547","type":"journal-article","created":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T10:25:53Z","timestamp":1751192753000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Psychosocial Determinants and Atopic Dermatitis Outcomes: A Cross\u2010Sectional Study From an Australian Paediatric Centre"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0694-2379","authenticated-orcid":false,"given":"Ashling","family":"Courtney","sequence":"first","affiliation":[{"name":"Eastern Health Clinical School Monash University  Box Hill Victoria Australia"},{"name":"Department of Dermatology Eastern Health  Melbourne Victoria Australia"},{"name":"Murdoch Children's Research Institute  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anousha","family":"Yazdabadi","sequence":"additional","affiliation":[{"name":"Eastern Health Clinical School Monash University  Box Hill Victoria Australia"},{"name":"Department of Dermatology Eastern Health  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Schembri","sequence":"additional","affiliation":[{"name":"Eastern Health Clinical School Monash University  Box Hill Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian J.","family":"Lowe","sequence":"additional","affiliation":[{"name":"Murdoch Children's Research Institute  Melbourne Victoria Australia"},{"name":"Allergy and Lung Health Unit, Melbourne School of Population and Global Health University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Crystal","family":"Williams","sequence":"additional","affiliation":[{"name":"Royal Melbourne Hospital  Melbourne Victoria Australia"},{"name":"Townsville University Hospital  Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John C.","family":"Su","sequence":"additional","affiliation":[{"name":"Eastern Health Clinical School Monash University  Box Hill Victoria Australia"},{"name":"Department of Dermatology Eastern Health  Melbourne Victoria Australia"},{"name":"Murdoch Children's Research Institute  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,12]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.14276"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.03.017"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13061602"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12113812"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.14755"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.13630"},{"volume-title":"Rural and Remote Health [Internet]","year":"2024","author":"Australian Institute of Health and Welfare","key":"e_1_2_12_8_1"},{"key":"e_1_2_12_9_1","unstructured":"https:\/\/www.health.gov.au\/sites\/default\/files\/documents\/2021\/12\/national\u2010preventive\u2010health\u2010strategy\u20102021\u20102030_1.pdf."},{"key":"e_1_2_12_10_1","unstructured":"Vulnerable Children \u201cDepartment of Health. 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