{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T16:45:39Z","timestamp":1780677939120,"version":"3.54.1"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T00:00:00Z","timestamp":1761350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T00:00:00Z","timestamp":1761350400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Nickel is the most common cause of allergic contact dermatitis (ACD). In certain geographical locations, the prevalence of nickel dermatitis (NiACD) has changed over time; however, there is little data on the prevalence of NiACD in Australia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate the prevalence and trends of both nickel contact allergy and NiACD in Australia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A retrospective audit was performed of 3582 patients patch tested to 5% nickel sulphate between 2014 and 2023. Relevance was assessed by consultant dermatologists. Patch test data was analysed using Pearson's\n                      <jats:italic>\u03c7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      test and Cochran\u2010Armitage\n                      <jats:italic>\u03c7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      test for trend.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      573\/3582 (16.0%) of patients had nickel contact allergy based on positive patch tests, while 169 (4.7%) of patients were diagnosed with NiACD, where exposure to nickel correlated with their presenting dermatitis. There was a significant trend of decreasing NiACD from 2014 to 2023 (\u03c7\n                      <jats:sup>2<\/jats:sup>\n                      <jats:sub>Trend<\/jats:sub>\n                      (1,\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u20093582)\u2009=\u200914.1239,\n                      <jats:italic>P<\/jats:italic>\n                      <jats:sub>Trend<\/jats:sub>\n                      \u2009=\u20090.0002, slope\u2009=\u2009\u22120.0045); however, there was no decline in the prevalence of nickel contact allergy (Pearson's\n                      <jats:italic>\u03c7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      test (9,\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u20093582)\u2009=\u200913.426,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.1443). Occupational NiACD was diagnosed in 20\/169 (11.8%). There was a high degree of comorbid atopic dermatitis (37.3%), asthma (24.9%), and allergic rhinitis (52.1%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We report a declining prevalence of NiACD but a stable prevalence of nickel contact allergy in our patient population between 2014 and 2023.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ajd.14611","type":"journal-article","created":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T08:10:26Z","timestamp":1761379826000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Nickel Contact Allergy in an Australian Patch Testing Centre Over 2014\u20132023"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-2857-0907","authenticated-orcid":false,"given":"Thomas R.","family":"Brasher","sequence":"first","affiliation":[{"name":"Occupational Dermatology Research and Education Centre Skin Health Institute  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Palmer","sequence":"additional","affiliation":[{"name":"Occupational Dermatology Research and Education Centre Skin Health Institute  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosemary","family":"Nixon","sequence":"additional","affiliation":[{"name":"Occupational Dermatology Research and Education Centre Skin Health Institute  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,25]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13327"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.12788\/cutis.0156"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/tx9002726"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0048-9697(94)90404-9"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14772"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.134.10.1231"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12846"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.09.058"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12775"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12556"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.12186"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14212"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.electacta.2022.141332"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.31925\/farmacia.2024.6.5"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2010.01702.x"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2751"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2011.10055"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.04.015"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjd\/ljad488"},{"key":"e_1_2_11_21_1","unstructured":"J.Cahill 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