{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:18:52Z","timestamp":1787843932761,"version":"build-2784847793"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Biologic therapies have transformed the management of inflammatory dermatologic conditions, including atopic dermatitis, psoriasis, hidradenitis suppurativa, and chronic spontaneous urticaria. However, studies in Australia and abroad highlight reduced uptake in regional areas, underscoring the need to address inequities in access.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method(s)<\/jats:title>\n                    <jats:p>A retrospective audit was performed of adult patients prescribed Pharmaceutical Benefits Scheme (PBS) subsidised biologics for severe atopic dermatitis, chronic plaque psoriasis, hidradenitis suppurativa, or chronic spontaneous urticaria between 1 January 2022 and 31 July 2025. Complete biologic treatment histories were collected for all identified patients, including prescriptions initiated before or continuing after the study period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 372 patients received PBS\u2010subsidised biologic medications for severe atopic dermatitis (42.7%), chronic spontaneous urticaria (25.8%), chronic plaque psoriasis (22.0%), and hidradenitis suppurativa (9.4%). Approximately 17% of all patients lived in regional\/remote areas (Modified Monash Model [MMM] 3\u20135). Dupilumab (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009159) and omalizumab (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200996) were the most commonly prescribed first\u2010line biologics overall. While wait times for appointments and biologic initiation were comparable across rurality classifications (median 72\u201377\u2009days to first appointment, 226\u2013304\u2009days to first biologic), patients from MMM 3\u20135 regions faced significantly higher costs per appointment (MMM 3\u20135 $110, MMM 2 $53 and MMM 1 $36).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study highlights regional disparities in biologic therapy access within an Australian tertiary dermatology service. Addressing these inequities is vital to achieving equitable and sustainable dermatologic care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ajd.70141","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T06:23:42Z","timestamp":1779344622000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Retrospective Review of Real\u2010World Patterns of Biologic Use in Dermatology Across Metropolitan, Regional and Rural Settings"],"prefix":"10.1111","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6784-5663","authenticated-orcid":false,"given":"N.","family":"Abeysekera","sequence":"first","affiliation":[{"name":"Department of Dermatology Sunshine Coast University Hospital  Birtinya Queensland Australia"},{"name":"The Skin Lab  Brisbane Queensland Australia"},{"name":"Population Health Department QIMR Berghofer Medical Research Institute  Brisbane Queensland Australia"},{"name":"School of Public Health University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Sibanda","sequence":"additional","affiliation":[{"name":"Department of Dermatology Sunshine Coast University Hospital  Birtinya Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Dermatology Sunshine Coast University Hospital  Birtinya Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Griffin","sequence":"additional","affiliation":[{"name":"Department of Dermatology Sunshine Coast University Hospital  Birtinya Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Wagner","sequence":"additional","affiliation":[{"name":"Department of Dermatology Sunshine Coast University Hospital  Birtinya Queensland Australia"},{"name":"The Skin Lab  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Banney","sequence":"additional","affiliation":[{"name":"Department of Dermatology Sunshine Coast University Hospital  Birtinya Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.26712"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.14388"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.18773\/austprescr.2025.026"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.13124"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.14525"},{"key":"e_1_2_11_7_1","volume-title":"Position Paper\u2014Chronic Spontaneous Urticaria","author":"Australasian Society of Clinical Immunology and Allergy","year":"2020"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2025.11.084"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-54447-5"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12237234"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/JW9.0000000000000130"},{"key":"e_1_2_11_12_1","unstructured":"P.Foley \u201cRural Patients within the Australasian Dermatology Registry [Conference Presentation]. Australasian College of Dermatologists Rural Dermatology Meeting \u201d(2024)https:\/\/australasiandermatologyregistry.org.au\/wp\u2010content\/uploads\/2024\/10\/Foley\u2010Rural\u2010Patients\u2010within\u2010the\u2010Australasian\u2010Dermatology\u2010Registry\u2010ACD\u2010Rural\u20102024.pdf."},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.14315"},{"key":"e_1_2_11_14_1","volume-title":"Modified Monash Model","author":"Australian Government","year":"2025"},{"key":"e_1_2_11_15_1","volume-title":"Distance to Work (Ranges) (DTWP)","author":"Australian Bureau of Statistics","year":"2021"},{"key":"e_1_2_11_16_1","volume-title":"Employee Earnings","author":"Statistics ABo","year":"2025"},{"key":"e_1_2_11_17_1","volume-title":"PTSS Subsidies","author":"Queensland Government","year":"2025"},{"key":"e_1_2_11_18_1","volume-title":"Sunshine Coast University Hospital Parking and Public Transport","author":"Sunshine Coast Hospital and Health Service","year":"2025"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.17236"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2024.2365820"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adengl.2019.03.016"},{"key":"e_1_2_11_22_1","volume-title":"Moderate to Severe Hidradenitis Suppurativa\u2014Continuing Authority Application Form (PB219)","author":"Australian Government","year":"2025"},{"key":"e_1_2_11_23_1","volume-title":"Federal Pre\u2010Budget Submission 2021\u201322","author":"Australasian College of Dermatologists","year":"2021"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.14096"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.70141","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ajd.70141","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajd.70141","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:33:38Z","timestamp":1787841218000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajd.70141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,20]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1111\/ajd.70141"],"URL":"https:\/\/doi.org\/10.1111\/ajd.70141","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,20]]},"assertion":[{"value":"2026-02-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}