{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T11:06:22Z","timestamp":1792062382936,"version":"4.4.0"},"reference-count":145,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T00:00:00Z","timestamp":1373414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Rep Immunol"],"published-print":{"date-parts":[[2013,8]]},"abstract":"\n Problem<\/jats:title>\n \n Maternal anti\u2010fetal rejection is a mechanism of disease in spontaneous preterm labor. The objective of this study was to determine whether the presence of human leukocyte antigen (\n HLA<\/jats:styled-content>\n ) panel\u2010reactive antibodies (PRA) during the second trimester increases the risk of spontaneous preterm delivery.\n <\/jats:p>\n <\/jats:sec>\n \n Methods of study<\/jats:title>\n \n This longitudinal case\u2010control study included pregnant women with spontaneous preterm deliveries (\n n<\/jats:italic>\n = 310) and control patients with normal term pregnancies (\n n<\/jats:italic>\n = 620), matched for maternal age and gravidity. Maternal plasma samples obtained at 14\u201316, 16\u201320, 20\u201324, and 24\u201328\u00a0weeks of gestation were analyzed for\n HLA<\/jats:styled-content>\n class\n I<\/jats:styled-content>\n and class\n II PRA<\/jats:styled-content>\n positivity using flow cytometry. The fetal\n HLA<\/jats:styled-content>\n genotype and maternal\n HLA<\/jats:styled-content>\n alloantibody epitope were determined for a subset of patients with positive\n HLA PRA<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n (i) Patients with spontaneous preterm delivery were more likely to exhibit\n HLA<\/jats:styled-content>\n class\n I<\/jats:styled-content>\n (adjusted\n OR\u00a0<\/jats:styled-content>\n =\u00a02.54,\n \n P<\/jats:styled-content>\n \u00a0\n <\/jats:italic>\n <\n \u00a0<\/jats:italic>\n 0.0001) and class\n II<\/jats:styled-content>\n (adjusted\n OR<\/jats:styled-content>\n \u00a0=\u00a01.98,\n \n P<\/jats:styled-content>\n \u00a0\n <\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 0.002)\n PRA<\/jats:styled-content>\n positivity than those delivering at term; (ii)\n HLA<\/jats:styled-content>\n class\n I PRA<\/jats:styled-content>\n positivity for patients with spontaneous preterm delivery between 28 and 34\u00a0weeks (adjusted\n OR<\/jats:styled-content>\n \u00a0=\u00a02.88;\n \n P<\/jats:styled-content>\n \u00a0\n <\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 0.001) and after 34\u00a0weeks of gestation (adjusted\n OR<\/jats:styled-content>\n \u00a0=\u00a02.53;\n \n P<\/jats:styled-content>\n \u00a0\n <\/jats:italic>\n <\n \u00a0<\/jats:italic>\n 0.0001) was higher than for those delivering at term; (iii)\n HLA<\/jats:styled-content>\n class\n II PRA<\/jats:styled-content>\n positivity for patients with spontaneous preterm delivery after 34\u00a0weeks of gestation was higher than for those delivering at term (adjusted\n OR<\/jats:styled-content>\n \u00a0=\u00a02.04;\n \n P<\/jats:styled-content>\n \u00a0\n <\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 0.002); (iv) multiparous women were at a higher risk for\n HLA<\/jats:styled-content>\n class\n I PRA<\/jats:styled-content>\n positivity than nulliparous women (adjusted\n OR<\/jats:styled-content>\n \u00a0=\u00a00.097,\n \n P<\/jats:styled-content>\n \u00a0\n <\/jats:italic>\n <\n \u00a0<\/jats:italic>\n 0.0001 for nulliparity); (v) nulliparous women had a higher rate of\n HLA<\/jats:styled-content>\n class\n I PRA<\/jats:styled-content>\n positivity with advancing gestational age (\n \n P<\/jats:styled-content>\n \u00a0\n <\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 0.001); and (vi) 78% of women whose fetuses were genotyped had alloantibodies specific against fetal\n HLA<\/jats:styled-content>\n class\n I<\/jats:styled-content>\n antigens.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Pregnant women with positive\n HLA<\/jats:styled-content>\n class\n I<\/jats:styled-content>\n or class\n II PRA<\/jats:styled-content>\n during the second trimester are at an increased risk of spontaneous preterm delivery due to antibody\u2010mediated maternal anti\u2010fetal rejection.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/aji.12141","type":"journal-article","created":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T08:07:18Z","timestamp":1373443638000},"page":"162-175","source":"Crossref","is-referenced-by-count":51,"title":["Detection of Anti\u2010\n HLA<\/scp>\n Antibodies in Maternal Blood in the Second Trimester to Identify Patients at Risk of Antibody\u2010Mediated Maternal Anti\u2010Fetal Rejection and Spontaneous Preterm Delivery"],"prefix":"10.1111","volume":"70","author":[{"given":"JoonHo","family":"Lee","sequence":"first","affiliation":[{"name":"Perinatology Research Branch NICHD\/NIH\/DHHS Bethesda MD and Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Romero","sequence":"additional","affiliation":[{"name":"Perinatology Research Branch NICHD\/NIH\/DHHS Bethesda MD and Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Xu","sequence":"additional","affiliation":[{"name":"Perinatology Research Branch NICHD\/NIH\/DHHS Bethesda MD and Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jezid","family":"Miranda","sequence":"additional","affiliation":[{"name":"Perinatology Research Branch NICHD\/NIH\/DHHS Bethesda MD and Detroit MI USA"},{"name":"Department of Obstetrics and Gynecology Wayne State University School of Medicine Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wonsuk","family":"Yoo","sequence":"additional","affiliation":[{"name":"Biostatistics and Epidemiology Division Department of Preventive Medicine University of Tennessee Health Science Center Memphis TN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piya","family":"Chaemsaithong","sequence":"additional","affiliation":[{"name":"Perinatology Research Branch NICHD\/NIH\/DHHS Bethesda MD and Detroit MI USA"},{"name":"Department of Obstetrics and Gynecology Wayne State University School of Medicine Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Pedro","family":"Kusanovic","sequence":"additional","affiliation":[{"name":"Perinatology Research Branch NICHD\/NIH\/DHHS Bethesda MD and Detroit MI USA"},{"name":"Department of Obstetrics and Gynecology School of Medicine Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"},{"name":"Center for Research and Innovation in Maternal\u2010Fetal Medicine (CIMAF) S\u00f3tero del R\u00edo Hospital Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tinnakorn","family":"Chaiworapongsa","sequence":"additional","affiliation":[{"name":"Perinatology Research Branch NICHD\/NIH\/DHHS Bethesda MD and Detroit MI USA"},{"name":"Department of Obstetrics and Gynecology Wayne State University School of Medicine Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adi L.","family":"Tarca","sequence":"additional","affiliation":[{"name":"Perinatology Research Branch NICHD\/NIH\/DHHS Bethesda MD and Detroit MI USA"},{"name":"Department of Computer Science Wayne State University Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Korzeniewski","sequence":"additional","affiliation":[{"name":"Perinatology Research Branch NICHD\/NIH\/DHHS Bethesda MD and Detroit MI USA"},{"name":"Department of Obstetrics and Gynecology Wayne State University School of Medicine Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia S.","family":"Hassan","sequence":"additional","affiliation":[{"name":"Perinatology Research Branch NICHD\/NIH\/DHHS Bethesda MD and Detroit MI USA"},{"name":"Department of Obstetrics and Gynecology Wayne State University School of Medicine Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nandor Gabor","family":"Than","sequence":"additional","affiliation":[{"name":"Perinatology Research Branch NICHD\/NIH\/DHHS Bethesda MD and Detroit MI USA"},{"name":"Department of Obstetrics and Gynecology Wayne State University School of Medicine Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo Hyun","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Seoul National University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong Jai","family":"Kim","sequence":"additional","affiliation":[{"name":"Perinatology Research Branch NICHD\/NIH\/DHHS Bethesda MD and Detroit MI USA"},{"name":"Department of Pathology Asan Medical Center University of Ulsan College of Medicine Seoul Korea"},{"name":"Department of Pathology Wayne State University School of Medicine Hutzel Women's Hospital Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,10]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"1","article-title":"Births: final data for 2005","volume":"56","author":"Martin JA","year":"2007","journal-title":"Natl Vital Stat Rep"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60074-4"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781444317619.ch4"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00575.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61856-X"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-2386"},{"key":"e_1_2_6_8_1","first-page":"544","volume-title":"Maternal\u2010Fetal Medicine: Principles and Practice","author":"Iams JD","year":"2009"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2006.01120.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-0528.2003.00021.x"},{"key":"e_1_2_6_11_1","first-page":"28","volume-title":"Preterm Birth","author":"Romero R","year":"2004"},{"key":"e_1_2_6_12_1","first-page":"29","volume-title":"Preterm Labor","author":"Romero R","year":"1997"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1994.tb21771.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)91063-I"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0095-5108(18)30286-0"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.1994.tb01115.x"},{"key":"e_1_2_6_17_1","first-page":"85","volume-title":"Preterm Labour","author":"Gomez R","year":"1997"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod67.4.1337"},{"key":"e_1_2_6_19_1","first-page":"375","article-title":"Infection of the amniotic cavity with Ureaplasma urealyticum in the midtrimester of pregnancy","volume":"40","author":"Horowitz S","year":"1995","journal-title":"J Reprod Med"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpm.2010.040"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.10.600"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI114583"},{"key":"e_1_2_6_23_1","first-page":"97","volume-title":"Preterm Birth: Causes, Prevention, and Management","author":"Romero R","year":"1993"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(89)90172-5"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-956773"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3016.2001.00007.x"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)91106-M"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(92)91845-2"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(91)90450-6"},{"key":"e_1_2_6_30_1","first-page":"262","article-title":"Infection in the pathogenesis of preterm labor","volume":"12","author":"Romero R","year":"1988","journal-title":"Semin Perinatol"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(91)90423-O"},{"key":"e_1_2_6_32_1","first-page":"205","article-title":"Interleukin 6 determination in the detection of microbial invasion of the amniotic cavity","volume":"167","author":"Romero R","year":"1992","journal-title":"Ciba Found Symp"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0002-9378(03)00839-1"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2001.118162"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1000289"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2010.00830.x"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.11.026"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.11.047"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.02.007"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(87)90153-0"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(89)90916-2"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(94)00420-I"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(03)00403-4"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0002-9378(03)00838-X"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767050500217863"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(95)02602-9"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767050902994838"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200107000-00011"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.grf.0000142512.38733.8c"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70713-1"},{"key":"e_1_2_6_51_1","first-page":"1","article-title":"Cervix, incompetence and premature labor","volume":"3","author":"Romero R","year":"1993","journal-title":"Fetus"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.12.002"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1515\/JPM.2006.002"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2000.106851"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.2773"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2001.00437.x"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)91084-P"},{"key":"e_1_2_6_58_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2001.116753"},{"key":"e_1_2_6_59_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.194"},{"key":"e_1_2_6_60_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-2310"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.1369\/jhc.5A6759.2006"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(94)90474-X"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-0077"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767050600949829"},{"key":"e_1_2_6_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(95)00306-C"},{"key":"e_1_2_6_66_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767050903168465"},{"key":"e_1_2_6_67_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767050903177193"},{"key":"e_1_2_6_68_1","doi-asserted-by":"publisher","DOI":"10.2350\/10-07-0867-OA.1"},{"key":"e_1_2_6_69_1","doi-asserted-by":"publisher","DOI":"10.1159\/000135701"},{"key":"e_1_2_6_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.06.092"},{"key":"e_1_2_6_71_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0016806"},{"key":"e_1_2_6_72_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0803834"},{"key":"e_1_2_6_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.2825"},{"key":"e_1_2_6_74_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2010.73"},{"key":"e_1_2_6_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1817"},{"key":"e_1_2_6_76_1","doi-asserted-by":"publisher","DOI":"10.1586\/eci.10.14"},{"key":"e_1_2_6_77_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000153298.48353.A4"},{"key":"e_1_2_6_78_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200205150-00001"},{"key":"e_1_2_6_79_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e318186ac4a"},{"key":"e_1_2_6_80_1","doi-asserted-by":"crossref","first-page":"842141","DOI":"10.1155\/2012\/842141","article-title":"The major histocompatibility complex in transplantation","volume":"2012","author":"Ayala Garcia MA","year":"2012","journal-title":"J Transplant"},{"key":"e_1_2_6_81_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2009.072371"},{"key":"e_1_2_6_82_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200002150-00001"},{"key":"e_1_2_6_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2009.06.015"},{"key":"e_1_2_6_84_1","doi-asserted-by":"publisher","DOI":"10.1186\/2001-1326-2-6"},{"key":"e_1_2_6_85_1","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2003.142"},{"key":"e_1_2_6_86_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2010.03383.x"},{"key":"e_1_2_6_87_1","doi-asserted-by":"publisher","DOI":"10.1385\/IR:36:1:255"},{"key":"e_1_2_6_88_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2008.00872.x"},{"key":"e_1_2_6_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-2498(01)00422-3"},{"key":"e_1_2_6_90_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200004150-00027"},{"key":"e_1_2_6_91_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2004.00360.x"},{"key":"e_1_2_6_92_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200301150-00008"},{"key":"e_1_2_6_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2006.07.011"},{"key":"e_1_2_6_94_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2011.01066.x"},{"key":"e_1_2_6_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2003.10.016"},{"key":"e_1_2_6_96_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-6143.2003.00072.x"},{"key":"e_1_2_6_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2012.12.005"},{"key":"e_1_2_6_98_1","doi-asserted-by":"publisher","DOI":"10.2350\/12-05-1195-OA.1"},{"key":"e_1_2_6_99_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.00900805"},{"key":"e_1_2_6_100_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2008.01955.x"},{"key":"e_1_2_6_101_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000256337.18347.aa"},{"key":"e_1_2_6_102_1","doi-asserted-by":"publisher","DOI":"10.1093\/biomet\/73.1.13"},{"key":"e_1_2_6_103_1","first-page":"1","article-title":"The R package Geepack for generalized estimating equations","volume":"15","author":"Hojsgaard S","year":"2005","journal-title":"J Stat Softw"},{"key":"e_1_2_6_104_1","doi-asserted-by":"publisher","DOI":"10.1203\/01.pdr.0000246074.73342.1e"},{"key":"e_1_2_6_105_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.178.6.3345"},{"key":"e_1_2_6_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.imlet.2007.09.014"},{"key":"e_1_2_6_107_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-1-119"},{"key":"e_1_2_6_108_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni1317"},{"key":"e_1_2_6_109_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-2896.2006.00408.x"},{"key":"e_1_2_6_110_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0000382"},{"key":"e_1_2_6_111_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2007.00510.x"},{"key":"e_1_2_6_112_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2008.00655.x"},{"key":"e_1_2_6_113_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1200406"},{"key":"e_1_2_6_114_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2010.00836.x"},{"key":"e_1_2_6_115_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2011.01049.x"},{"key":"e_1_2_6_116_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.12077"},{"key":"e_1_2_6_117_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcibr1207279"},{"key":"e_1_2_6_118_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.171.3.1376"},{"key":"e_1_2_6_119_1","doi-asserted-by":"publisher","DOI":"10.1053\/plac.1999.0496"},{"key":"e_1_2_6_120_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.281.5380.1191"},{"key":"e_1_2_6_121_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm_00000411"},{"key":"e_1_2_6_122_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.158.9.4122"},{"key":"e_1_2_6_123_1","doi-asserted-by":"publisher","DOI":"10.1159\/000087963"},{"key":"e_1_2_6_124_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1680"},{"key":"e_1_2_6_125_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.107.060632"},{"key":"e_1_2_6_126_1","doi-asserted-by":"publisher","DOI":"10.1615\/CritRevImmunol.v25.i5.30"},{"key":"e_1_2_6_127_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2011.04038.x"},{"key":"e_1_2_6_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jri.2010.01.005"},{"key":"e_1_2_6_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(03)00334-7"},{"key":"e_1_2_6_130_1","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.4049\/jimmunol.138.5.1408","article-title":"Transfer of antibodies directed to paternal major histocompatibility class I antigens from pregnant mice to the developing fetus","volume":"138","author":"Adeniyi\u2010Jones SC","year":"1987","journal-title":"J Immunol"},{"key":"e_1_2_6_131_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2004.00500.x"},{"key":"e_1_2_6_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2007.03.002"},{"key":"e_1_2_6_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jri.2010.05.006"},{"key":"e_1_2_6_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2008.09.017"},{"key":"e_1_2_6_135_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.06.085"},{"key":"e_1_2_6_136_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrdd.10008"},{"key":"e_1_2_6_137_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2001.117680"},{"key":"e_1_2_6_138_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-199203000-00005"},{"key":"e_1_2_6_139_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200208270-00018"},{"key":"e_1_2_6_140_1","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1182\/blood.V23.5.621.621","article-title":"Mechanisms of Isoimmunization. I. The Transplacental Passage of Fetal Erythrocytes in Homospecific Pregnancies","volume":"23","author":"Cohen F","year":"1964","journal-title":"Blood"},{"key":"e_1_2_6_141_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1990.30490273444.x"},{"key":"e_1_2_6_142_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198212000-00010"},{"key":"e_1_2_6_143_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.1.75"},{"key":"e_1_2_6_144_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a137325"},{"key":"e_1_2_6_145_1","first-page":"241","article-title":"Clinical and anti\u2010HLA antibody profile of nine renal transplant recipients with failed grafts: donor\u2010specific and non\u2010donor\u2010specific antibody development","author":"Rebellato LM","year":"2006","journal-title":"Clin Transpl"},{"key":"e_1_2_6_146_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2008.00755.x"}],"container-title":["American Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faji.12141","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aji.12141","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T08:13:03Z","timestamp":1696493583000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aji.12141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,10]]},"references-count":145,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1111\/aji.12141"],"URL":"https:\/\/doi.org\/10.1111\/aji.12141","archive":["Portico"],"relation":{},"ISSN":["1046-7408","1600-0897"],"issn-type":[{"value":"1046-7408","type":"print"},{"value":"1600-0897","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,10]]}}}