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Inflammation proteins measured in baby's blood on postnatal days 1, 7, and 14 were considered elevated if in the top quartile for gestational age. Logistic regression models adjusting for potential confounders assessed odds ratios.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared to mothers with neither <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CVI<\/jats:styled-content>, those with <jats:styled-content style=\"fixed-case\">CVI<\/jats:styled-content> were more likely to have infants with elevated <jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> SAA<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> MPO<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> IL<\/jats:styled-content>\u20101\u03b2, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20106, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20106R, <jats:styled-content style=\"fixed-case\">TNF<\/jats:styled-content>\u2010\u03b1, <jats:styled-content style=\"fixed-case\">RANTES<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> ICAM<\/jats:styled-content>\u20103, E\u2010selectin, and <jats:styled-content style=\"fixed-case\">VEGF<\/jats:styled-content>\u2010R2 on day 1; those with <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content> were more likely to have infants with elevated <jats:styled-content style=\"fixed-case\">MPO<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> IL<\/jats:styled-content>\u20106R, <jats:styled-content style=\"fixed-case\">TNF<\/jats:styled-content>\u2010R1, <jats:styled-content style=\"fixed-case\">TNF<\/jats:styled-content>\u2010R2, and <jats:styled-content style=\"fixed-case\">RANTES<\/jats:styled-content> on day 7. Placental anaerobes and genital mycoplasma were more common in pregnancies with <jats:styled-content style=\"fixed-case\">CVI<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Gestational <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CVI<\/jats:styled-content> should be targeted for preventing systemic inflammation in the very preterm newborn.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aji.12313","type":"journal-article","created":{"date-parts":[[2014,8,28]],"date-time":"2014-08-28T05:59:29Z","timestamp":1409205569000},"page":"162-174","source":"Crossref","is-referenced-by-count":33,"title":["Systemic Inflammation in the Extremely Low Gestational Age Newborn Following Maternal Genitourinary Infections"],"prefix":"10.1111","volume":"73","author":[{"given":"Raina N.","family":"Fichorova","sequence":"first","affiliation":[{"name":"Laboratory of Genital Tract Biology Department of Obstetrics, Gynecology and Reproductive Biology Brigham and Women's Hospital and Harvard Medical School Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noah","family":"Beatty","sequence":"additional","affiliation":[{"name":"Laboratory of Genital Tract Biology Department of Obstetrics, Gynecology and Reproductive Biology Brigham and Women's Hospital and Harvard Medical School Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita R. 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