{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T21:14:08Z","timestamp":1783977248262,"version":"3.55.0"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,3,15]],"date-time":"2015-03-15T00:00:00Z","timestamp":1426377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000833","name":"Rosetrees Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000833","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000306","name":"Tommy's Baby Charity","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000306","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NIHR Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust and King's College London"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Rep Immunol"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:p>There is a growing interest in the role of antimicrobial peptides (AMPs) in the female reproductive tract during pregnancy. This commentary highlights recent advances in the field including those of Itakoa and colleagues who have demonstrated elafin and secretory leukocyte protease inhibitor (SLPI) expression in cervical cells from pregnant women during pregnancy. They suggest that these specific AMPs may be raised in women in true preterm labour. This complements other studies exploring the use cervico\u2010vaginal fluid elafin and other antimicrobial peptides as biomarkers to predict risk of spontaneous preterm birth early in pregnancy. With continued focus on the contribution and regulation of these important small peptides in pregnancy, the potential of AMPs as clinical tools for identifying women most at risk of spontaneous preterm birth should soon be realised.<\/jats:p>","DOI":"10.1111\/aji.12379","type":"journal-article","created":{"date-parts":[[2015,3,16]],"date-time":"2015-03-16T03:56:59Z","timestamp":1426478219000},"page":"123-125","source":"Crossref","is-referenced-by-count":14,"title":["Small Peptides with a Big Role: Antimicrobial Peptides in the Pregnant Female Reproductive Tract"],"prefix":"10.1111","volume":"74","author":[{"given":"Rachel M.","family":"Tribe","sequence":"first","affiliation":[{"name":"Women's Health Academic Centre King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,3,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.12354"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2011.00970.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0100771"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP-10-0537"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.07.010"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2014.07.004"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro976"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmu065"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2006.01.006"},{"key":"e_1_2_6_11_1","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1165\/rcmb.2013-0238OC","article-title":"Functional characterization of polymorphisms in the peptidase inhibitor 3 (elafin) gene and validation of their contribution to risk of acute respiratory distress syndrome","volume":"51","author":"Tejera P","year":"2014","journal-title":"Am J Respir Cell Mol Biol"}],"container-title":["American Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faji.12379","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aji.12379","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T16:47:12Z","timestamp":1695574032000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aji.12379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,15]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["10.1111\/aji.12379"],"URL":"https:\/\/doi.org\/10.1111\/aji.12379","archive":["Portico"],"relation":{},"ISSN":["1046-7408","1600-0897"],"issn-type":[{"value":"1046-7408","type":"print"},{"value":"1600-0897","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,15]]}}}