{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T03:05:43Z","timestamp":1777518343943,"version":"3.51.4"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,5,24]],"date-time":"2016-05-24T00:00:00Z","timestamp":1464048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP #86721"],"award-info":[{"award-number":["MOP #86721"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Rep Immunol"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:sec><jats:title>Problem<\/jats:title><jats:p>Cervical biopsies offer a unique opportunity for studying local immune response. To investigate hormonally induced immune fluctuations in cervical tissues of Kenyan female sex workers, we improved biopsy sampling protocol safety. Here, we report on steps taken to minimize exposure to HIV following two cervical biopsies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods of study<\/jats:title><jats:p>Women were asked to abstain from vaginal intercourse to limit HIV exposure during wound healing with financial compensation. A comprehension tool for informed consent, on\u2010site detection of prostate\u2010specific antigens indicating unprotected intercourse within 48 hr, and bi\u2010weekly text message reminders were implemented.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The implemented methods improved compliance with post\u2010procedure abstinence by two times (<jats:italic>P<\/jats:italic> = 0.013). Fourteen days following a cervical biopsy, no sign of genital inflammation or change in HIV T\u2010cell target proportion were observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study provides new tools for limiting HIV exposure in studies requiring biopsy sampling among women at risk of acquiring HIV.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aji.12520","type":"journal-article","created":{"date-parts":[[2016,5,25]],"date-time":"2016-05-25T04:56:19Z","timestamp":1464152179000},"page":"82-93","source":"Crossref","is-referenced-by-count":17,"title":["Improving Adherence to Post\u2010Cervical Biopsy Sexual Abstinence in Kenyan Female Sex Workers"],"prefix":"10.1111","volume":"76","author":[{"given":"Julie","family":"Lajoie","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology University of Manitoba Winnipeg MB Canada"},{"name":"Department of Community Health Sciences University of Manitoba Winnipeg MB Canada"},{"name":"Department of Medical Microbiology University of Nairobi Nairobi Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genevieve","family":"Boily\u2010Larouche","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology University of Manitoba Winnipeg MB Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelsie","family":"Doering","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology University of Manitoba Winnipeg MB Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliana","family":"Cheruiyot","sequence":"additional","affiliation":[{"name":"Kenya AIDS Control Program Nairobi Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julius","family":"Oyugi","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology University of Manitoba Winnipeg MB Canada"},{"name":"Department of Medical Microbiology University of Nairobi Nairobi Kenya"},{"name":"Kenya AIDS Control Program Nairobi Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina","family":"Broliden","sequence":"additional","affiliation":[{"name":"Department of Medicine Solna Center for Molecular Medicine Clinic of Infectious Diseases Karolinska University Hospital Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Kimani","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology University of Manitoba Winnipeg MB Canada"},{"name":"Department of Medical Microbiology University of Nairobi Nairobi Kenya"},{"name":"Kenya AIDS Control Program Nairobi Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith R.","family":"Fowke","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology University of Manitoba Winnipeg MB Canada"},{"name":"Department of Community Health Sciences University of Manitoba Winnipeg MB Canada"},{"name":"Department of Medical Microbiology University of Nairobi Nairobi Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2302"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2011.0239"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2011.0240"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2012.0276"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1101836"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3791\/51906"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0047570"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ298"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2012.7"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiu023"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-7824(99)00013-X"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-10-141"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/sti.77.2.84"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2009.03.014"}],"container-title":["American Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faji.12520","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aji.12520","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aji.12520","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aji.12520","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T23:47:38Z","timestamp":1696376858000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aji.12520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,24]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1111\/aji.12520"],"URL":"https:\/\/doi.org\/10.1111\/aji.12520","archive":["Portico"],"relation":{},"ISSN":["1046-7408","1600-0897"],"issn-type":[{"value":"1046-7408","type":"print"},{"value":"1600-0897","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,24]]}}}