{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T10:22:33Z","timestamp":1774520553589,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,11,8]],"date-time":"2016-11-08T00:00:00Z","timestamp":1478563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Rep Immunol"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec><jats:title>Problem<\/jats:title><jats:p>The effects of chronic glomerulonephritis (<jats:styled-content style=\"fixed-case\">CGN<\/jats:styled-content>) on semen quality and cytokine levels in the semen of infertile males remain undetermined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method of study<\/jats:title><jats:p>Fifty\u2010eight semen samples from normal males and <jats:styled-content style=\"fixed-case\">CGN<\/jats:styled-content> males with and without infertility, respectively, were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Semen volume, semen <jats:styled-content style=\"fixed-case\">pH<\/jats:styled-content>, sperm density, percentage of forward movement of sperm, sperm activate rate, sperm survival rate, and rate of normal sperm morphology of infertility males with <jats:styled-content style=\"fixed-case\">CGN<\/jats:styled-content> were significantly lower than those of <jats:styled-content style=\"fixed-case\">CGN<\/jats:styled-content> males without infertility and normal males (<jats:italic>P<\/jats:italic>&lt;.05). In addition, the blood urea nitrogen and serum creatinine levels and interleukin (<jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>)\u201017 and <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201018 levels in infertility males with <jats:styled-content style=\"fixed-case\">CGN<\/jats:styled-content> were significantly higher than those of <jats:styled-content style=\"fixed-case\">CGN<\/jats:styled-content> males without infertility and normal males (<jats:italic>P<\/jats:italic>&lt;.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">CGN<\/jats:styled-content> increased the blood urea nitrogen and serum creatinine levels, which induced abnormal expression of <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201017 and <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201018, and negatively affected male semen quality and might result in male infertility.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aji.12598","type":"journal-article","created":{"date-parts":[[2016,11,8]],"date-time":"2016-11-08T08:17:39Z","timestamp":1478593059000},"source":"Crossref","is-referenced-by-count":7,"title":["Effect of chronic glomerulonephritis on the semen quality and cytokines in the semen of infertile males"],"prefix":"10.1111","volume":"77","author":[{"given":"Huina","family":"Zhang","sequence":"first","affiliation":[{"name":"Reproductive center The 2<sup>nd<\/sup> Affiliated Hospital &amp; Yuying Children's Hospital of Wenzhou Medical University  Wenzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingfen","family":"Ying","sequence":"additional","affiliation":[{"name":"Reproductive center The 2<sup>nd<\/sup> Affiliated Hospital &amp; Yuying Children's Hospital of Wenzhou Medical University  Wenzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yilu","family":"Chen","sequence":"additional","affiliation":[{"name":"Reproductive center The 2<sup>nd<\/sup> Affiliated Hospital &amp; Yuying Children's Hospital of Wenzhou Medical University  Wenzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaosheng","family":"Lu","sequence":"additional","affiliation":[{"name":"Reproductive center The 2<sup>nd<\/sup> Affiliated Hospital &amp; Yuying Children's Hospital of Wenzhou Medical University  Wenzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonggang","family":"Huang","sequence":"additional","affiliation":[{"name":"Reproductive center The 2<sup>nd<\/sup> Affiliated Hospital &amp; Yuying Children's Hospital of Wenzhou Medical University  Wenzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,11,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00272-5"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.17116\/terarkh201587634-39"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJNRD.S93866"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2016.05.031"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/0886022X.2015.1014756"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.55.5409"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.5049\/EBP.2015.13.2.41"},{"key":"e_1_2_6_9_1","first-page":"71","article-title":"Renal anemia and cardiac remodeling in patient with chronic glomerulonephritis","volume":"85","author":"Murkamilov IT","year":"2013","journal-title":"Ter Arkh"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.140954"},{"key":"e_1_2_6_11_1","volume-title":"WHO Laboratory Manual for the Examination of Human Semen and Sperm\u2010Cervical Mucus Interactions","author":"World Health Organization","year":"1992"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004170050144"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.183.6.2593"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2013.12.005"},{"key":"e_1_2_6_15_1","first-page":"5672","article-title":"The relationship between IL\u201017 and male infertility: semen analysis","volume":"6","author":"Qian L","year":"2011","journal-title":"Afr J Microbiol Res"}],"container-title":["American Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faji.12598","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faji.12598","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aji.12598","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T16:12:03Z","timestamp":1695571923000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aji.12598"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,8]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1111\/aji.12598"],"URL":"https:\/\/doi.org\/10.1111\/aji.12598","archive":["Portico"],"relation":{},"ISSN":["1046-7408","1600-0897"],"issn-type":[{"value":"1046-7408","type":"print"},{"value":"1600-0897","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,8]]},"article-number":"e12598"}}