{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T20:57:56Z","timestamp":1789851476464,"version":"4.0.1"},"reference-count":66,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,11,28]],"date-time":"2017-11-28T00:00:00Z","timestamp":1511827200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007397","name":"Univerzita Karlova v Praze","doi-asserted-by":"publisher","award":["PROGRES Q40"],"award-info":[{"award-number":["PROGRES Q40"]}],"id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Rep Immunol"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:p>In this study, pentraxin 3 (PTX3), C\u2010reactive protein (CRP), and serum amyloid P component (SAP) concentrations in the amniotic fluid of women with preterm pre\u2010labor rupture of membranes (PPROM) were evaluated based on evidence of microbial invasion of the amniotic cavity (MIAC), intra\u2010amniotic inflammation (IAI), and microbial\u2010associated IAI. A total of 149 women with PPROM were included in this study. Amniotic fluid samples were obtained by transabdominal amniocentesis. Amniotic fluid PTX3, SAP, and CRP concentrations were assessed using enzyme\u2010linked immunosorbent assay. PTX3 and CRP concentrations were higher in women with MIAC, IAI, and microbial\u2010associated IAI than in women without these conditions. SAP concentrations were only higher in the presence of IAI and microbial\u2010associated IAI. Amniotic fluid PTX3 concentrations of 11\u00a0ng\/mL were found to be the best value for identifying the presence of microbial\u2010associated IAI and IAI in women with PPROM. To conclude, amniotic fluid pentraxins are involved in intra\u2010amniotic inflammatory responses in pregnancies complicated by PPROM.<\/jats:p>","DOI":"10.1111\/aji.12789","type":"journal-article","created":{"date-parts":[[2017,11,29]],"date-time":"2017-11-29T15:57:35Z","timestamp":1511971055000},"source":"Crossref","is-referenced-by-count":24,"title":["Amniotic fluid pentraxins: Potential early markers for identifying intra\u2010amniotic inflammatory complications in preterm pre\u2010labor rupture of membranes"],"prefix":"10.1111","volume":"79","author":[{"given":"Ivana","family":"Musilova","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Faculty of Medicine Hradec Kralove University Hospital Hradec Kralove Charles University in Prague  Hradec Kralove Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ctirad","family":"Andrys","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology and Allergy Faculty of Medicine Hradec Kralove University Hospital Hradec Kralove Charles University in Prague  Hradec Kralove Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Krejsek","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology and Allergy Faculty of Medicine Hradec Kralove University Hospital Hradec Kralove Charles University in Prague  Hradec Kralove Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela","family":"Drahosova","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology and Allergy Faculty of Medicine Hradec Kralove University Hospital Hradec Kralove Charles University in Prague  Hradec Kralove Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbora","family":"Zednikova","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology and Allergy Faculty of Medicine Hradec Kralove University Hospital Hradec Kralove Charles University in Prague  Hradec Kralove Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenka","family":"Pliskova","sequence":"additional","affiliation":[{"name":"Institute of Clinical Biochemistry and Diagnostics University Hospital Hradec Kralove  Hradec Kralove Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"Zemlickova","sequence":"additional","affiliation":[{"name":"Institute of Clinical Microbiology Faculty of Medicine Hradec Kralove University Hospital in Hradec Kralove Charles University  Hradec Kralove Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Jacobsson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Sahlgrenska Academy Gothenburg University  Gothenburg Sweden"},{"name":"Division of Health Data and Digitalisation Department of Genetics and Bioinformatics Norwegian Institute of Public Health  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9858-7900","authenticated-orcid":false,"given":"Marian","family":"Kacerovsky","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Faculty of Medicine Hradec Kralove University Hospital Hradec Kralove Charles University in Prague  Hradec Kralove Czech Republic"},{"name":"Biomedical Research Center University Hospital Hradec Kralove  Hradec Kralove Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,11,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200301000-00033"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogc.2005.03.003"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2014.958463"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0133929"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2017.07.012"},{"key":"e_1_2_6_7_1","doi-asserted-by":"crossref","DOI":"10.1111\/aji.12668","article-title":"Uterine tissue aging and adverse reproductive outcomes: new concepts, mechanisms, and markers","volume":"77","author":"Menon R","year":"2017","journal-title":"Am J Reprod Immunol"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0182731"},{"key":"e_1_2_6_9_1","article-title":"Cervical fluid interleukin 6 and intra\u2010amniotic complications of preterm prelabor rupture of membranes","author":"Musilova I","year":"2017","journal-title":"J Matern Fetal Neonatal Med"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.12723"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767050902994663"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2008.00620.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.07.009"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature07201"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.02.029"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12476"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2016.04.007"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.23.021704.115756"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-030409-101305"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016340902971441"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.11.018"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2012.09.009"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpm.2009.141"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2014.11.010"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2012.07.016"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2009.10.018"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(96)00339-0"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2007.01385.x"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2009.09.017"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0150217"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2012.27.6.674"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1080\/003655101753267937"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1258\/ebm.2012.011312"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2mb25081k"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767050903551509"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2014.02.006"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000224607.46622.bc"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2311"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2014.947574"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1080\/14786430500362231"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1600-0412.2003.00223.x"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2016.1237499"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2016.1255192"},{"key":"e_1_2_6_44_1","doi-asserted-by":"crossref","first-page":"385 e381","DOI":"10.1016\/j.ajog.2014.03.069","article-title":"Bedside assessment of amniotic fluid interleukin\u20106 in preterm prelabor rupture of membranes","volume":"211","author":"Kacerovsky M","year":"2014","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0119355"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.32.2.335-351.1994"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2015.1006620"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2015.1006621"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.2307\/2531595"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.52.4.561"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196507152730306"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)41653-5"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4419-0901-5_7"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2009.01019.x"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.119628"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1515\/JPM.2005.093"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.1MR0114-068R"},{"key":"e_1_2_6_58_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2002.004796"},{"key":"e_1_2_6_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2015.03.179"},{"key":"e_1_2_6_60_1","doi-asserted-by":"publisher","DOI":"10.1529\/biophysj.105.080382"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2156"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1854"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016340802572646"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2009.12.023"},{"key":"e_1_2_6_65_1","doi-asserted-by":"crossref","first-page":"342 e341","DOI":"10.1016\/j.ajog.2012.01.004","article-title":"The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation","volume":"206","author":"Kacerovsky M","year":"2012","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_6_66_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0085277"},{"key":"e_1_2_6_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2005.05.009"}],"container-title":["American Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faji.12789","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aji.12789","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T20:11:27Z","timestamp":1694549487000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aji.12789"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,28]]},"references-count":66,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["10.1111\/aji.12789"],"URL":"https:\/\/doi.org\/10.1111\/aji.12789","archive":["Portico"],"relation":{},"ISSN":["1046-7408","1600-0897"],"issn-type":[{"value":"1046-7408","type":"print"},{"value":"1600-0897","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,28]]},"article-number":"e12789"}}