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It makes up over 98% of ectopic pregnancy (EP), which is the leading cause of maternal morbidity and mortality in the first trimester of pregnancy. Immune cells at the maternal\u2010fetal interface play important roles in the process of embryo implantation, stroma decidualization, and early placental development. Alterations in the composition, phenotype, and activity of the immune cells in the fallopian tubes contribute toward the onset of TEP. In this review, we compare the leukocytic proportions in decidua of normal pregnancy, and in decidua and fallopian tubes of TEP. The possible functions of these immune cells in the pathophysiology of TEP are also discussed.<\/jats:p>","DOI":"10.1111\/aji.13093","type":"journal-article","created":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T16:44:03Z","timestamp":1548348243000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Alteration of the immune cell profiles in the pathophysiology of tubal ectopic pregnancy"],"prefix":"10.1111","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4339-8907","authenticated-orcid":false,"given":"Xia","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Obstetrics &amp; Gynaecology The University of Hong Kong Hong Kong SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheuk\u2010Lun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynaecology The University of Hong Kong Hong Kong SAR China"},{"name":"Department of Obstetrics and Gynaecology, Shenzhen Key Laboratory of Fertility Regulation The University of Hong Kong\u2010Shenzhen Hospital Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond H. 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