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Because of its characteristic localization patterns and molecular functions, syndecan\u20101 has been identified as a biomarker of plasmacyte, and syndecan\u20101 immunohistochemistry (IHC) becomes the most dependable diagnostic method for CE. In this review, we discuss the association between CE and reproductive failure, the clinicopathological characterization of CE, the function and expression of syndecan\u20101, the progress of syndecan\u20101 IHC in the diagnosis of CE, and the prediction of reproductive outcome.<\/jats:p>","DOI":"10.1111\/aji.13255","type":"journal-article","created":{"date-parts":[[2020,4,24]],"date-time":"2020-04-24T05:31:20Z","timestamp":1587706280000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Chronic endometritis and reproductive failure: Role of syndecan\u20101"],"prefix":"10.1111","volume":"84","author":[{"given":"Yanhong","family":"Xu","sequence":"first","affiliation":[{"name":"Center for Reproductive Medicine Drum Tower Clinic Medical College of Nanjing Medical University Nanjing China"},{"name":"Department of Obstetrics and Gynecology Center for Reproductive Medicine The Affiliated Drum Tower Hospital of Nanjing 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