{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T20:23:39Z","timestamp":1787862219159,"version":"build-2784847793"},"reference-count":181,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,5,28]],"date-time":"2020-05-28T00:00:00Z","timestamp":1590624000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Rep Immunol"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Myeloid\u2010derived suppressor cells (MDSCs) are a heterogeneous group of myeloid\u2010origin cells which have immunosuppressive activities in several conditions, such as cancer and inflammation. Recent research has also associated MDSCs with numerous obstetrical and gynecological diseases. During pregnancy, MDSCs accumulate to ensure maternal\u2010fetal immune tolerance, whereas they are decreased in patients who suffer from early miscarriage or pre\u2010eclampsia. While the etiology of endometriosis is still unknown, abnormal accumulation of MDSCs in the peripheral blood and peritoneal fluid, alongside an increased level of reactive oxygen species (ROS), has been observed in these patients, which is central to the cellular immune regulations by MDSCs. Additionally, the regulation of MDSCs observed in tumours is also applicable to gynecologic neoplasms, including ovarian cancer and cervical cancer. More recently, emerging evidence has shown that there are high levels of MDSCs in premature ovarian failure (POF) and in vitro fertilization (IVF), but the underlying mechanisms are unknown. In this review, the generation and mechanisms of MDSCs are summarized. In particular, the modulation of these cells in immune\u2010related obstetrical and gynecological diseases is discussed, including potential treatment options targeting MDSCs.<\/jats:p>","DOI":"10.1111\/aji.13266","type":"journal-article","created":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T10:55:11Z","timestamp":1589712911000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Myeloid\u2010derived suppressor cells in obstetrical and gynecological diseases"],"prefix":"10.1111","volume":"84","author":[{"given":"Zi\u2010Meng","family":"Zheng","sequence":"first","affiliation":[{"name":"Insitute of Obstetrics and Gynecology Hospital of Obstetrics and Gynecology Fudan University Shanghai China"},{"name":"NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research) Hospital of Obstetrics and Gynecology Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui\u2010Li","family":"Yang","sequence":"additional","affiliation":[{"name":"Insitute of Obstetrics and Gynecology Hospital of Obstetrics and Gynecology Fudan University Shanghai China"},{"name":"NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research) Hospital of Obstetrics and Gynecology Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen\u2010Zhen","family":"Lai","sequence":"additional","affiliation":[{"name":"Insitute of Obstetrics and Gynecology Hospital of Obstetrics and Gynecology Fudan University Shanghai China"},{"name":"NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research) Hospital of Obstetrics and Gynecology Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng\u2010Jie","family":"Wang","sequence":"additional","affiliation":[{"name":"Insitute of Obstetrics and Gynecology Hospital of Obstetrics and Gynecology Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao\u2010Liang","family":"Yang","sequence":"additional","affiliation":[{"name":"Insitute of Obstetrics and Gynecology Hospital of Obstetrics and Gynecology Fudan University Shanghai China"},{"name":"NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research) Hospital of Obstetrics and Gynecology Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9276-0722","authenticated-orcid":false,"given":"Ming\u2010Qing","family":"Li","sequence":"additional","affiliation":[{"name":"Insitute of Obstetrics and Gynecology Hospital of Obstetrics and Gynecology Fudan University Shanghai China"},{"name":"NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research) Hospital of Obstetrics and Gynecology Fudan University Shanghai China"},{"name":"Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases Hospital of Obstetrics and Gynecology Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6493-4086","authenticated-orcid":false,"given":"Jun","family":"Shao","sequence":"additional","affiliation":[{"name":"Insitute of Obstetrics and Gynecology Hospital of Obstetrics and Gynecology Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,28]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-4505"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-1299"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-3755"},{"issue":"1","key":"e_1_2_11_5_1","first-page":"100","article-title":"Hematopoiesis and suppressor bone marrow cells in mice bearing large metastatic Lewis lung carcinoma tumors","volume":"47","author":"Young MR","year":"1987","journal-title":"Cancer Res"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-3037"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2506"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms12150"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.2119\/molmed.2010.00178"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0802740"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2018.09.001"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellimm.2019.103990"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.b.21206"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.8.5791"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.aaf8943"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.4161\/21624011.2014.954829"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2015.1004983"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.12493"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-017-0504-y"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2018.07.004"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-08-237412"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13238-015-0237-2"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2016.516"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12272-016-0822-9"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-15-0004"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI68189"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12185-015-1761-9"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1089\/jir.2015.0174"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1601722"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-017-1963-5"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1200068"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-35723-8_8"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.20164"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.6839"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbcan.2014.04.003"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2016.01.014"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201142092"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2017.86"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.35205"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1301309"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.00475"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/now034"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.01804"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2010.05.010"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI60083"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-018-1654-4"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-11-2772"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2013.00052"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1402004"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13277-015-4477-9"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3175"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.26075"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02499"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2015.06.002"},{"issue":"12","key":"e_1_2_11_55_1","first-page":"4756","article-title":"Activated granulocytes and granulocyte\u2010derived hydrogen peroxide are the underlying mechanism of suppression of t\u2010cell function in advanced cancer patients","volume":"61","author":"Schmielau J","year":"2001","journal-title":"Cancer Res"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1103553"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.3109\/08830185.2012.755176"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1609"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28622"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-1491"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-09-2587"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1400833"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1201449"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-017-2774-x"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.17375"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20101956"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-16-0144"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2016.01.004"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001471"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20131916"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.1038\/cgt.2016.19"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1612920114"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2016.1247135"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.imlet.2017.10.001"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-019-0306-1"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.1111\/imm.12036"},{"key":"e_1_2_11_77_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.182.1.240"},{"key":"e_1_2_11_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200939486"},{"key":"e_1_2_11_79_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19051468"},{"key":"e_1_2_11_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.imlet.2017.07.003"},{"key":"e_1_2_11_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2017.01.016"},{"key":"e_1_2_11_82_1","doi-asserted-by":"publisher","DOI":"10.1038\/cmi.2014.46"},{"key":"e_1_2_11_83_1","doi-asserted-by":"publisher","DOI":"10.1089\/dna.2015.2962"},{"key":"e_1_2_11_84_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201344200"},{"key":"e_1_2_11_85_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gaw026"},{"key":"e_1_2_11_86_1","doi-asserted-by":"publisher","DOI":"10.1038\/cmi.2015.41"},{"key":"e_1_2_11_87_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.1HI1016-306RR"},{"key":"e_1_2_11_88_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.13099"},{"key":"e_1_2_11_89_1","doi-asserted-by":"publisher","DOI":"10.1111\/cei.12790"},{"key":"e_1_2_11_90_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.1A1015-481RR"},{"key":"e_1_2_11_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jri.2018.05.002"},{"key":"e_1_2_11_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.09.018"},{"key":"e_1_2_11_93_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.12351"},{"key":"e_1_2_11_94_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1500340"},{"key":"e_1_2_11_95_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.13081"},{"key":"e_1_2_11_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2012.07.017"},{"key":"e_1_2_11_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-018-1251-0"},{"key":"e_1_2_11_98_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-1642-x"},{"key":"e_1_2_11_99_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.14825"},{"key":"e_1_2_11_100_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.00161"},{"key":"e_1_2_11_101_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.12492"},{"key":"e_1_2_11_102_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201646564"},{"key":"e_1_2_11_103_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep19916"},{"key":"e_1_2_11_104_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI122182"},{"key":"e_1_2_11_105_1","doi-asserted-by":"publisher","DOI":"10.1111\/imm.12224"},{"key":"e_1_2_11_106_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4467"},{"key":"e_1_2_11_107_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.01098"},{"key":"e_1_2_11_108_1","doi-asserted-by":"publisher","DOI":"10.1111\/imm.12751"},{"key":"e_1_2_11_109_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-018-0008-5"},{"key":"e_1_2_11_110_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.13067"},{"key":"e_1_2_11_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2017.03.026"},{"key":"e_1_2_11_112_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201747417"},{"key":"e_1_2_11_113_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-16-0297"},{"key":"e_1_2_11_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2019.05.014"},{"key":"e_1_2_11_115_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719118808923"},{"key":"e_1_2_11_116_1","doi-asserted-by":"publisher","DOI":"10.1038\/cmi.2009.102"},{"key":"e_1_2_11_117_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2014.414"},{"key":"e_1_2_11_118_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deu172"},{"key":"e_1_2_11_119_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP-17-0342"},{"key":"e_1_2_11_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2011.03.009"},{"key":"e_1_2_11_121_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201142335"},{"key":"e_1_2_11_122_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-2354"},{"key":"e_1_2_11_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.imlet.2018.10.011"},{"key":"e_1_2_11_124_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-17-3962"},{"key":"e_1_2_11_125_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.35128"},{"key":"e_1_2_11_126_1","doi-asserted-by":"publisher","DOI":"10.3109\/09513590.2011.588753"},{"key":"e_1_2_11_127_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathmechdis-012419-032654"},{"key":"e_1_2_11_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2013.10.023"},{"key":"e_1_2_11_129_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-019-03056-x"},{"key":"e_1_2_11_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2004.08.031"},{"key":"e_1_2_11_131_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0103249"},{"key":"e_1_2_11_132_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.9270"},{"key":"e_1_2_11_133_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12307-013-0133-3"},{"key":"e_1_2_11_134_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmz018"},{"key":"e_1_2_11_135_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-17-0691"},{"key":"e_1_2_11_136_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-14-0635"},{"key":"e_1_2_11_137_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2019-00350"},{"key":"e_1_2_11_138_1","doi-asserted-by":"publisher","DOI":"10.5114\/ceji.2017.72823"},{"key":"e_1_2_11_139_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.00691"},{"key":"e_1_2_11_140_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03966-7"},{"key":"e_1_2_11_141_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.23020"},{"key":"e_1_2_11_142_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-11-2449"},{"key":"e_1_2_11_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.09.018"},{"key":"e_1_2_11_144_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.01608"},{"key":"e_1_2_11_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.08.025"},{"key":"e_1_2_11_146_1","article-title":"Myeloid\u2010derived suppressor cells promote epithelial ovarian cancer cell stemness by inducing the CSF2\/p\u2010STAT3 signalling pathway","author":"Li X","journal-title":"Febs J"},{"key":"e_1_2_11_147_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-017-1997-8"},{"key":"e_1_2_11_148_1","doi-asserted-by":"publisher","DOI":"10.4161\/21624011.2014.962397"},{"key":"e_1_2_11_149_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2016.197"},{"key":"e_1_2_11_150_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-16-0387"},{"key":"e_1_2_11_151_1","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2014.998519"},{"issue":"4","key":"e_1_2_11_152_1","first-page":"1580","article-title":"Intraperitoneal neutrophils activated by KRAS\u2010induced ovarian cancer exert antitumor effects by modulating adaptive immunity","volume":"53","author":"Yoshida M","year":"2018","journal-title":"Int J Oncol"},{"key":"e_1_2_11_153_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-018-1412-6"},{"key":"e_1_2_11_154_1","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2018.1465166"},{"key":"e_1_2_11_155_1","doi-asserted-by":"publisher","DOI":"10.1136\/ijgc-2019-000521"},{"key":"e_1_2_11_156_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-17-0740"},{"key":"e_1_2_11_157_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-11-215"},{"key":"e_1_2_11_158_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-019-0725-x"},{"key":"e_1_2_11_159_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-19-0880"},{"key":"e_1_2_11_160_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-17-2460"},{"key":"e_1_2_11_161_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-019-01795-9"},{"key":"e_1_2_11_162_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.12095"},{"key":"e_1_2_11_163_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.13300"},{"key":"e_1_2_11_164_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.29647"},{"key":"e_1_2_11_165_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep18217"},{"key":"e_1_2_11_166_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dju147"},{"key":"e_1_2_11_167_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.26347"},{"key":"e_1_2_11_168_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-17-2472"},{"key":"e_1_2_11_169_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0213184"},{"key":"e_1_2_11_170_1","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-15-0742"},{"key":"e_1_2_11_171_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-014-1537-8"},{"key":"e_1_2_11_172_1","article-title":"Murine oviductal high\u2010grade serous carcinomas mirror the genomic alterations, gene expression profiles, and immune microenvironment of their human counterparts","author":"McCool K","year":"2019","journal-title":"Can Res"},{"key":"e_1_2_11_173_1","first-page":"1","article-title":"Abnormal aggregation of myeloid\u2010derived suppressor cells in a mouse model of cyclophosphamide\u2010induced premature ovarian failure","author":"Han M","year":"2019","journal-title":"Gynecol Endocrinol"},{"key":"e_1_2_11_174_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00521"},{"key":"e_1_2_11_175_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2017.1400002"},{"key":"e_1_2_11_176_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40425-017-0243-4"},{"key":"e_1_2_11_177_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2018.03.015"},{"key":"e_1_2_11_178_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-018-2175-3"},{"issue":"12","key":"e_1_2_11_179_1","doi-asserted-by":"crossref","first-page":"3220","DOI":"10.1158\/0008-5472.CAN-17-3415","article-title":"Blockade of myeloid\u2010derived suppressor cell expansion with all\u2010 retinoic acid increases the efficacy of antiangiogenic therapy","volume":"78","author":"Bauer R","year":"2018","journal-title":"Can Res"},{"key":"e_1_2_11_180_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2017-314032"},{"key":"e_1_2_11_181_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature21676"},{"key":"e_1_2_11_182_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jri.2015.11.001"}],"container-title":["American Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aji.13266","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aji.13266","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aji.13266","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T10:02:00Z","timestamp":1693908120000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aji.13266"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,28]]},"references-count":181,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10.1111\/aji.13266"],"URL":"https:\/\/doi.org\/10.1111\/aji.13266","archive":["Portico"],"relation":{},"ISSN":["1046-7408","1600-0897"],"issn-type":[{"value":"1046-7408","type":"print"},{"value":"1600-0897","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,28]]},"assertion":[{"value":"2020-03-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13266"}}