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The dysregulation of the spiral artery and inadequate trophoblast invasion lead to PE symptoms through producing various inflammatory cytokines and anti\u2010angiogenic factors from the placenta. T lymphocytes play a special role in the epithelium and stroma of the human endometrium. CD4+ T helper (Th) cells, Th1\/Th2, and Th17\/T regulatory (Treg) balance mainly contribute to the establishment of a pregnancy\u2010favorable environment. This review examined the dysregulation of some cytokines produced from T cells, the dysregulation of the transcription factors of Th cells, the expression of chemokine receptors on T cells, as well as the effects of some factors including vitamin D on the activity of T cells, and finally, the dysregulation of various miRNAs related to T cells, which could cause PE.<\/jats:p>","DOI":"10.1111\/aji.13475","type":"journal-article","created":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T17:25:56Z","timestamp":1622136356000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["T lymphocytes and preeclampsia: The potential role of T\u2010cell subsets and related MicroRNAs in the pathogenesis of preeclampsia"],"prefix":"10.1111","volume":"86","author":[{"given":"Mohammad Ali","family":"Zolfaghari","sequence":"first","affiliation":[{"name":"Molecular Medicine Research Center Tabriz University of Medical Sciences Tabriz 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