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The maternal gut microbiome is remodeled during pregnancy, and this, coupled with the maternal nutrient intake during gestation shapes the production of metabolites that can cross the placenta and affect fetal development. As posited by the Developmental Origins of Health and Disease Hypothesis, such environmental influences can have major effects on the developing organ systems. When occurring at particularly sensitive gestational time points, these developmental programming events can have long lasting effects on offspring adaptation to the postnatal environment, and major health implications later in life. This review will summarize current knowledge on how pregnancy and maternal dietary intake intrinsically and extrinsically modify maternal gut microbiota composition and metabolite production. Further, we will assess how these factors shape the fetal landscape and ultimately contribute to offspring health.<\/jats:p>\n                  <jats:p>DOHaD, fetal development, metabolites, microbiome, nutrition, pregnancy, short\u2010chain fatty acids<\/jats:p>","DOI":"10.1111\/aji.13802","type":"journal-article","created":{"date-parts":[[2023,12,12]],"date-time":"2023-12-12T09:32:07Z","timestamp":1702373527000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Nutrition during pregnancy: Influence on the gut microbiome and fetal development"],"prefix":"10.1111","volume":"91","author":[{"given":"Gabriela","family":"Barrientos","sequence":"first","affiliation":[{"name":"Laboratory of Experimental Medicine Hospital Alem\u00e1n  Buenos Aires Argentina"},{"name":"National Scientific and Technical Research Council (CONICET)  Buenos Aires 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