{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T01:30:52Z","timestamp":1769650252471,"version":"3.49.0"},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:00:00Z","timestamp":1767830400000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82071648"],"award-info":[{"award-number":["82071648"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Rep Immunol"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Problems<\/jats:title>\n                    <jats:p>To investigate the impact of anti\u2010endometrial antibodies (EMAb) on pregnancy outcomes in infertile patients undergoing in vitro fertilization (IVF) and to assess the potential value of personalized treatment strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method of Study<\/jats:title>\n                    <jats:p>A total of 47 EMAb\u2010positive and 166 EMAb\u2010negative oocyte retrieval cycles were retrospectively included following propensity score matching (PSM) to control for basic clinical characteristics influencing pregnancy outcomes. The two groups were compared in terms of various aspects closely associated with IVF outcomes. Pregnancy outcomes were assessed based on implantation, clinical pregnancy, miscarriage, and ongoing pregnancy rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      No significant differences were found between the two groups regarding infertility\u2010related clinical characteristics, oocyte\u2010 and embryo\u2010related indicators, endometriosis incidence, and so forth. Compared with the EMAb\u2010negative group, the implantation rate in the EMAb\u2010positive group was lower by 10.3 percentage points (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.047), whereas the 8.2\u2010point lower clinical pregnancy rate did not reach statistical significance (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.234). There were no significant differences in ongoing pregnancy and miscarriage rates between the two groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our study observed that the presence of EMAb was associated with less favorable IVF outcomes, primarily reflected in lower implantation and clinical pregnancy rates. However, once the implantation was successful, the risk of miscarriage did not increase. These findings suggest a potential role for EMAb screening in guiding personalized treatment strategies, such as increasing the number of embryos transferred or using immunosuppressive agents, to improve IVF outcomes. Future research should involve more extensive and diverse populations to explore the mechanisms of action of EMAb and their impact on IVF treatment outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aji.70202","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T07:34:33Z","timestamp":1767944073000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Anti\u2010Endometrial Antibodies on IVF Implantation and Pregnancy Outcomes: A Retrospective Study"],"prefix":"10.1111","volume":"95","author":[{"given":"Xiaoxuan","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Reproductive Medicine Women's Hospital of Nanjing Medical University Nanjing Women and Children's Healthcare Hospital  Nanjing PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Reproductive Medicine Women's Hospital of Nanjing Medical University Nanjing Women and Children's Healthcare Hospital  Nanjing PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7358-2377","authenticated-orcid":false,"given":"Yaping","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Reproductive Medicine Women's Hospital of Nanjing Medical University Nanjing Women and Children's Healthcare Hospital  Nanjing PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mianqiu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Reproductive Medicine Women's Hospital of Nanjing Medical University Nanjing Women and Children's Healthcare Hospital  Nanjing PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Reproductive Medicine Women's Hospital of Nanjing Medical 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