{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T03:43:13Z","timestamp":1783309393522,"version":"3.54.6"},"reference-count":53,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["303206\/2022\u20105"],"award-info":[{"award-number":["303206\/2022\u20105"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Rep Immunol"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Problem<\/jats:title>\n                    <jats:p>Maternal obesity is associated with elevated inflammatory markers, hormonal dysregulation, and metabolic disturbances. However, how maternal obesity modulates systemic inflammatory, hormonal, and redox profiles in the peripartum and postpartum periods remains incompletely understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method of Study<\/jats:title>\n                    <jats:p>\n                      This observational study evaluated inflammatory biomarkers, steroid hormone levels, and oxidative stress markers in obese (\n                      <jats:italic>n<\/jats:italic>\n                      = 8) and non\u2010obese (\n                      <jats:italic>n<\/jats:italic>\n                      = 11) pregnant women undergoing labor induction. Peripheral maternal blood samples were collected immediately before induction and again within approximately 5\u201310 mins after delivery. Placental tissue was collected postpartum within the same interval. Comparative analyses between groups and time points were performed using repeated\u2010measures statistical models.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>C\u2010reactive protein (CRP) levels increased postpartum only in the obese group, indicating an enhanced inflammatory response after delivery. In contrast, interleukin\u20106 (IL\u20106) levels declined postpartum only in the non\u2010obese group. No between\u2010group differences were detected in the oxidative stress markers assessed, either in maternal blood or placental tissue.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Maternal obesity is associated with distinct postpartum inflammatory and hormonal profiles, characterized by sustained CRP elevation and altered cytokine dynamics. No between\u2010group differences were detected in the redox markers assessed, suggesting preserved redox balance in the parameters evaluated. These findings highlight the importance of considering postpartum immune modulation in obese parturients and support further investigation into obesity\u2010associated inflammatory regulation during the peripartum period.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aji.70227","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T14:28:20Z","timestamp":1773757700000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Maternal Obesity Modulates Postpartum Inflammatory and Hormonal Profiles, Without Detectable Differences in Tested Redox Markers"],"prefix":"10.1111","volume":"95","author":[{"given":"Juliana Augusta","family":"Dias","sequence":"first","affiliation":[{"name":"Faculdade De Medicina da Universidade Federal Dos Vales do Jequitinhonha e Mucuri  Diamantina Minas Gerais Brazil"},{"name":"Programa De P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade da Universidade Federal Dos Vales do Jequitinhonha e Mucuri  Diamantina Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabela Carvalho","family":"Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"Programa De P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade da Universidade Federal Dos Vales do Jequitinhonha e Mucuri  Diamantina Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vin\u00edcius Lopes","family":"Cantu\u00e1ria","sequence":"additional","affiliation":[{"name":"Faculdade De Medicina da Universidade Federal Dos Vales do Jequitinhonha e Mucuri  Diamantina Minas Gerais Brazil"},{"name":"Programa De P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade da Universidade Federal Dos Vales do Jequitinhonha e Mucuri  Diamantina Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna Oliveira","family":"Costa","sequence":"additional","affiliation":[{"name":"Programa De P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade da Universidade Federal Dos Vales do Jequitinhonha e Mucuri  Diamantina Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joyce Mirlane Moreira","family":"Costa","sequence":"additional","affiliation":[{"name":"Programa De P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade da Universidade Federal Dos Vales do Jequitinhonha e Mucuri  Diamantina Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna Caroline Chaves","family":"Garcia","sequence":"additional","affiliation":[{"name":"Programa De P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade da Universidade Federal Dos Vales do Jequitinhonha e Mucuri  Diamantina Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliane Duarte","family":"Santos","sequence":"additional","affiliation":[{"name":"Programa De P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade da Universidade Federal Dos Vales do Jequitinhonha e Mucuri  Diamantina Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lourdes Fernanda","family":"Godinho","sequence":"additional","affiliation":[{"name":"Programa De P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade da Universidade Federal Dos Vales do Jequitinhonha e Mucuri  Diamantina Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina Luiza Ba\u00eata","family":"Costa","sequence":"additional","affiliation":[{"name":"Programa De P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade da Universidade Federal Dos Vales do Jequitinhonha e Mucuri  Diamantina Minas Gerais 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