{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T06:10:43Z","timestamp":1778047843269,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,2,25]],"date-time":"2013-02-25T00:00:00Z","timestamp":1361750400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Maternal obesity is becoming more prevalent in obstetrics and has been linked with pregnancy complications and perinatal outcomes. The gradient of association of increasing maternal obesity and pregnancy outcome is less well studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To determine the influence of an increasing gradient of obesity, categorised by the body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>), on pregnancy outcomes and to determine the <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> thresholds at which pregnancy complications occur.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Secondary analysis of an observational study on pregnancy and obesity. The <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> at the first prenatal visit was grouped into <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> categories (&lt;18.5, 18.5\u201324.9, 25\u201329.9, 30\u201334.9, 35\u201339.9, 40\u201344.9, and \u226545) and compared with the normal category (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> 18.5\u201325) for pregnancy outcomes and adjusted for known cofounders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 4,490 women were stratified into the pre\u2010pregnancy <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> categories: &lt;18.5 (<jats:italic>n<\/jats:italic>\u00a0=\u00a0276), 18.5\u201324.9 (<jats:italic>n<\/jats:italic>\u00a0=\u00a01965), 25\u201329.9 (<jats:italic>n<\/jats:italic>\u00a0=\u00a01072), 30\u201334.9 (<jats:italic>n<\/jats:italic>\u00a0=\u00a0551), 35\u201339.9 (<jats:italic>n<\/jats:italic>\u00a0=\u00a0317), 40\u201344.9 (<jats:italic>n<\/jats:italic>\u00a0=\u00a0167), and \u226545 (<jats:italic>n<\/jats:italic>\u00a0=\u00a0142). The maternal demographics were significantly different between <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> groups (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Compared to women with a normal <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>, different <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> thresholds convey an increased risk for specific pregnancy complications: <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>\u226525 for gestational diabetes (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), induction of labour (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), caesarean delivery (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and large for gestational age neonate (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001); <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>\u226530 for pre\u2010eclampsia (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), wound infection (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001), shoulder dystocia (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and meconium (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.006); <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>\u226535 for urinary tract infection (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and postpartum haemorrhage (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001); <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>\u226540 for endometritis (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Body mass index thresholds exist at which pregnancy complications significantly increase and they vary depending on outcome ranging from <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> \u226525 to a <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> \u226540.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajo.12047","type":"journal-article","created":{"date-parts":[[2013,2,25]],"date-time":"2013-02-25T11:06:52Z","timestamp":1361790412000},"page":"250-257","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["The effects of an increasing gradient of maternal obesity on pregnancy outcomes"],"prefix":"10.1111","volume":"53","author":[{"given":"Everett F.","family":"Magann","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Arkansas for the Medical Sciences Little Rock Arkansas USA"},{"name":"School of Women's and Infants' Health University of Western Australia Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorota A.","family":"Doherty","sequence":"additional","affiliation":[{"name":"School of Women's and Infants' Health University of Western Australia Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam T.","family":"Sandlin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Arkansas for the Medical Sciences Little Rock Arkansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suneet P.","family":"Chauhan","sequence":"additional","affiliation":[{"name":"Eastern Virginia Medical School Norfolk Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John C.","family":"Morrison","sequence":"additional","affiliation":[{"name":"University of Mississippi Medical Center Jackson Mississippi USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,2,25]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"Centers for Disease Control (CDC)2012. 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