{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T16:35:48Z","timestamp":1768408548640,"version":"3.49.0"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,4,14]],"date-time":"2015-04-14T00:00:00Z","timestamp":1428969600000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Curtin University\u00e2\u20ac\u2122s Centre for Population Health Research"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>In <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia, high\u2010risk human papillomavirus (<jats:styled-content style=\"fixed-case\">HR HPV<\/jats:styled-content>) testing is recommended for follow\u2010up of women treated for a high\u2010grade squamous intra\u2010epithelial lesion (<jats:styled-content style=\"fixed-case\">HSIL<\/jats:styled-content>). The sensitivity of <jats:styled-content style=\"fixed-case\">HR HPV<\/jats:styled-content> testing is critical to identify women at risk of further high\u2010grade cervical disease. In <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia, this management protocol is known as the \u2018<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>est of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ure\u2019 (<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>o<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To conduct a population\u2010based study investigating practitioners' compliance with <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>o<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Women treated for an <jats:styled-content style=\"fixed-case\">HSIL<\/jats:styled-content> between the five\u2010year period 01 <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>an 2006 to 31 <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ec 2010 were identified and followed up for at least a 27\u2010month period. Proportions and relative odds were determined for women entering and completing the <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>o<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content> management pathway within recommended time frames.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 5,194 women identified as \u2018eligible\u2019 to enter the <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>o<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content> management pathway. Of these, 1,916 (37%) were managed with annual <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ap smears and never had a <jats:styled-content style=\"fixed-case\">HR HPV<\/jats:styled-content> test performed. There were 1,296 (25%) women who entered the <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>o<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content> management pathway within recommended time frames, and a further 1,978 (38%) women entered outside of the recommended time frames. Overall, 961 women completed the <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>o<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content> and were classified as \u2018cured\u2019 and were eligible to return to two\u2010yearly <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ap smears. Women's demographic information was significantly associated with <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>o<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content> commencement, specifically, age and year of treatment, and <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndex of <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>elative <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ocioeconomic <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>isadvantage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Overall, a significant number of <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralian women did not <jats:italic>enter<\/jats:italic> (~37%) and <jats:italic>complete<\/jats:italic> (~50%) the <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>o<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content> management pathway. The challenge remains to advocate its use to practitioners to ensure women are returned to the population screening interval in a timely manner.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajo.12309","type":"journal-article","created":{"date-parts":[[2015,4,14]],"date-time":"2015-04-14T07:59:33Z","timestamp":1428998373000},"page":"185-190","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The human papillomavirus <scp>T<\/scp>est of <scp>C<\/scp>ure: A lesson on compliance with the <scp>NHMRC<\/scp> guidelines on screening to prevent cervical cancer"],"prefix":"10.1111","volume":"55","author":[{"given":"Aime","family":"Munro","sequence":"first","affiliation":[{"name":"WA Cervical Cancer Prevention Program Women's Health Clinical Care Unit Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrina","family":"Spilsbury","sequence":"additional","affiliation":[{"name":"Centre for Population Health Research Curtin University Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yee","family":"Leung","sequence":"additional","affiliation":[{"name":"School of Women's and Infants' Health University of Western Australia Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"O'Leary","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Curtin University Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Williams","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences Curtin University Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim","family":"Codde","sequence":"additional","affiliation":[{"name":"Institute for Health Research University of Notre Dame Australia Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nerida","family":"Steel","sequence":"additional","affiliation":[{"name":"WA Cervical Cancer Prevention Program Women's Health Clinical Care Unit Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Cohen","sequence":"additional","affiliation":[{"name":"School of Women's and Infants' Health University of Western Australia Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Semmens","sequence":"additional","affiliation":[{"name":"Centre for Population Health Research Curtin University Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,14]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Screening to Prevent Cervical Cancer: Guidelines for the Management of Women with Screen Detected Abnormalities","author":"National Health and Medical Research Council","year":"2005"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2007.00965.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djp089"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(11)70078-X"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.2008.00567.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.06.095"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2007.00945.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.01748.x"},{"key":"e_1_2_9_10_1","first-page":"1","article-title":"A whole\u2010population profile of HPV testing as a test of cure for high\u2010grade cervical dysplasia in NSW, Australia","author":"Morrell S","year":"2014","journal-title":"J Med Screen"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2009.01132.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasc.2013.09.004"},{"key":"e_1_2_9_13_1","unstructured":"Australian Bureau of Statistics.Census of Population and Housing: Socio\u2010Economic Indexes for Areas (SEIFA) Australia \u2013 Data only 2006. 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