{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T11:27:35Z","timestamp":1776511655696,"version":"3.51.2"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,6,5]],"date-time":"2015-06-05T00:00:00Z","timestamp":1433462400000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Soonchunhyang University Research Fund"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Blood transfusions may be associated with risks and the risk: benefit ratio is not always clear, even in the setting of haemorrhage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To describe the management practices and outcomes in women with profound anaemia who refused blood transfusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Retrospective analysis over a 10\u2010year time frame of severely anaemic women (Hb &lt;50\u00a0g\/L) with benign conditions who had requested not to receive a blood transfusion. Demographic data, clinical presentation, anaemia management practice and serious adverse events were collected from the medical record charts. Women were analysed in two groups: a gynaecologic (Gyn) and an obstetric (Ob) population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 19 women (12 Gyn and 7 Ob) met the inclusion criteria with a mean age of 35.8\u00a0\u00b1\u00a010.2\u00a0years. The lowest mean Hb concentration was 41.3\u00a0\u00b1\u00a09.7\u00a0g\/L (Gyn Group) and 36.0\u00a0\u00b1\u00a08.9\u00a0g\/L (Ob Group) which increased, to 67.3\u00a0\u00b1\u00a014.3\u00a0g\/L and 73.1\u00a0\u00b1\u00a06.9\u00a0g\/L, respectively, by the time of hospital discharge. Anaemia management initially addressed the underlying etiology and was followed by intravenous iron (all cases) plus erythropoiesis stimulating agents, haemocoagulase and\/or fluids. The mean length of hospital stay was 10.5\u00a0\u00b1\u00a04.4 and 13.7\u00a0\u00b1\u00a04.1\u00a0days for the Gyn and Ob groups, respectively. No deaths or other serious complications occurred.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These findings suggest that young and otherwise healthy women can tolerate profound anaemia (Hb &lt;50\u00a0g\/L) permitting corrective strategies to be successfully implemented without the need for blood transfusion.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajo.12329","type":"journal-article","created":{"date-parts":[[2015,6,5]],"date-time":"2015-06-05T10:27:13Z","timestamp":1433500033000},"page":"262-267","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Avoiding unnecessary blood transfusions in women with profound anaemia"],"prefix":"10.1111","volume":"55","author":[{"given":"Eun Sil","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Soonchunhyang University Seoul Hospital Seoul 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