{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T03:24:37Z","timestamp":1791084277612,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,7,14]],"date-time":"2015-07-14T00:00:00Z","timestamp":1436832000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Evaluating cost\u2010effectiveness of induction of labour (<jats:styled-content style=\"fixed-case\">IOL<\/jats:styled-content>) using outpatient mechanical cervical ripening using a Foley catheter (<jats:styled-content style=\"fixed-case\">OFC<\/jats:styled-content>) compared to inpatient chemical ripening using prostin gel (<jats:styled-content style=\"fixed-case\">IPG<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Cost\u2010effectiveness analysis from a hospital perspective alongside a <jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content>. Women in a metropolitan Australian maternity hospital with an unfavourable cervix requiring <jats:styled-content style=\"fixed-case\">IOL<\/jats:styled-content> at term were randomised to <jats:styled-content style=\"fixed-case\">IPG<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a051) or <jats:styled-content style=\"fixed-case\">OFC<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a050). Primary economic measures were mean patient costs, incremental cost per predelivery inpatient hour prevented, and incremental cost per vaginal delivery within 12\u00a0h of admission to the birthing unit. Bootstrapping estimates were used to construct 95% confidence intervals. Estimates of net monetary benefit were calculated to aid interpretation of the results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean hospital costs per woman were nonsignificantly higher ($6524 <jats:styled-content style=\"fixed-case\">OFC<\/jats:styled-content> vs $5876 <jats:styled-content style=\"fixed-case\">IPG<\/jats:styled-content>) and mean difference $643; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> \u2212$366 to $1652. <jats:styled-content style=\"fixed-case\">OFC<\/jats:styled-content> group experienced fewer predelivery inpatient hours, resulting in an incremental cost per inpatient hour prevented of $57 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> \u2212$79.44 to $190.65). However, <jats:styled-content style=\"fixed-case\">OFC<\/jats:styled-content> patients were less likely to deliver vaginally within 12\u00a0h of admission to birthing unit. Other cost influencing clinical outcomes, including caesarean section rates and total inpatient hours, were not statistically different. Results were not sensitive to changes in costs or the cost\u2010effectiveness thresholds.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">OFC<\/jats:styled-content> had fewer inpatient hours and costs prior to birth. However, <jats:styled-content style=\"fixed-case\">OFC<\/jats:styled-content> did not reduce overall inpatient hours and failed to achieve comparable rates of vaginal delivery within 12\u00a0h of birthing unit admission. Therefore, <jats:styled-content style=\"fixed-case\">OFC<\/jats:styled-content> is unlikely to be considered cost\u2010effective compared to <jats:styled-content style=\"fixed-case\">IPG<\/jats:styled-content> in current hospital settings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajo.12348","type":"journal-article","created":{"date-parts":[[2015,7,14]],"date-time":"2015-07-14T17:17:06Z","timestamp":1436894226000},"page":"440-445","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Cost\u2010effectiveness of term induction of labour using inpatient prostaglandin gel versus outpatient Foley catheter"],"prefix":"10.1111","volume":"55","author":[{"given":"Kathryn","family":"Austin","sequence":"first","affiliation":[{"name":"Royal Hospital for Women Randwick New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgina M.","family":"Chambers","sequence":"additional","affiliation":[{"name":"National Perinatal Epidemiology and Statistics Unit School of Women's and Children's Health University of New South Wales (UNSW) Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"de Abreu Lourenco","sequence":"additional","affiliation":[{"name":"Centre for Health Economics Research and Evaluation University of Technology Ultimo New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arushi","family":"Madan","sequence":"additional","affiliation":[{"name":"School of Women's and Children's Health UNSW Medicine University of New South Wales (UNSW) Randwick New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniella","family":"Susic","sequence":"additional","affiliation":[{"name":"Royal Hospital for Women Randwick New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Henry","sequence":"additional","affiliation":[{"name":"Royal Hospital for Women Randwick New South Wales Australia"},{"name":"School of Women's and Children's Health UNSW Medicine University of New South Wales (UNSW) Randwick New South Wales Australia"},{"name":"Women's and Children's Health St George Hospital Kogarah New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,7,14]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"LiZ ZekiR HilderL SullivanEA.Australia's mothers and babies 2010. 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