{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T08:36:27Z","timestamp":1782203787106,"version":"3.54.5"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,5,2]],"date-time":"2016-05-02T00:00:00Z","timestamp":1462147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Shanghai Science and Technology Commission","award":["15140903000"],"award-info":[{"award-number":["15140903000"]}]},{"name":"Shanghai Municipal Commission of Health and Family Planning","award":["201540224"],"award-info":[{"award-number":["201540224"]}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Malignant ovarian germ cell tumours (<jats:styled-content style=\"fixed-case\">MOGCT<\/jats:styled-content>s) are usually detected at an early stage, with patients achieving a satisfactory prognosis. However, the role of staging surgery in the treatment of apparent early\u2010stage <jats:styled-content style=\"fixed-case\">MOGCT<\/jats:styled-content>s remains controversial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To investigate the role of staging procedures in apparent early\u2010stage patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We performed a retrospective review of 102 patients who were diagnosed with <jats:styled-content style=\"fixed-case\">MOGCT<\/jats:styled-content>s and had malignant lesions confined to their ovaries, between January 1997 and October 2014 at the Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China. Statistical analysis was carried out using <jats:styled-content style=\"fixed-case\">SPSS<\/jats:styled-content> software which included survival analysis by Kaplan\u2013Meier method and Fisher's exact test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three patients relapsed and one died. The five\u2010year overall survival rate and disease\u2010free survival rate were 98.7% and 96.4%, respectively. Eighty\u2010nine patients (87.3%) received adjuvant chemotherapy and only 23 patients (22.5%) were completely staged. In total, 3\/49 (6.1%), 1\/44 (2.3%) and 0\/49 (0.0%) patients were diagnosed with malignant cells in peritoneal fluid, pelvic lymph nodes and omentum, respectively. Positive tumour cells were not correlated with recurrence. Univariate analysis revealed that neither complete staging surgery nor individual factors were useful prognostic factors for disease\u2010free survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The staging surgery could be omitted for apparent early\u2010stage patients affected by <jats:styled-content style=\"fixed-case\">MOGCT<\/jats:styled-content>s without adverse impact upon survival.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajo.12468","type":"journal-article","created":{"date-parts":[[2016,5,2]],"date-time":"2016-05-02T16:27:34Z","timestamp":1462206454000},"page":"398-402","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["The role of staging surgery in the treatment of apparent early\u2010stage malignant ovarian germ cell tumours"],"prefix":"10.1111","volume":"56","author":[{"given":"Ting","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Gynecology 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