{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T18:40:14Z","timestamp":1790880014349,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,9,5]],"date-time":"2016-09-05T00:00:00Z","timestamp":1473033600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There are no contemporary cohorts examining pregnancy outcomes in women with type 2 diabetes (T2D) in Australia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      To compare pregnancy outcomes in women with and without T2D, and assess effects of body mass index (\n                      <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>\n                      ) and glycaemic control on outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>An historical cohort study was conducted of all singleton births &gt;\u00a020\u00a0weeks gestation at a specialist maternity network in Australia from 2010 to 2013. Data were extracted from the Birthing Outcomes System database. Multivariable logistic regression analysis was used to examine associations between presence of T2D and pregnancy outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Outcomes for 138 pregnancies with T2D and 27\u00a0075 pregnancies in women without diabetes were compared (type 1 diabetes and gestational diabetes excluded). Women with T2D were older and more overweight compared to women without diabetes (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.01). Their babies were born earlier (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.01) with increased risk of large for gestational age (adjusted odds ratio 2.13 (95% CI 1.37\u20133.32)), hypoglycaemia (4.90 (2.79\u20138.61)), jaundice (2.58 (1.61\u20134.13)) and shoulder dystocia (2.72 (1.09\u20136.78)), but not congenital malformations or perinatal death. Women with T2D had a higher risk of induction (4.03 (2.71\u20135.99)), caesarean section (2.10 (1.44\u20133.04)), preterm birth (2.74 (1.78\u20134.24)) and pre\u2010eclampsia (2.75 (1.49\u20135.10)). An HbA1c \u2265\u00a06.0% (42\u00a0mmol\/mol) was associated with increased preterm birth,\n                      <jats:styled-content style=\"fixed-case\">special care nursery<\/jats:styled-content>\n                      admission, hypoglycaemia and jaundice.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Despite availability of preconception care, good glycaemic control and specialist management, T2D remains associated with increased adverse obstetric and neonatal outcomes. Further research to examine predictors of adverse outcomes may assist in targeted antenatal surveillance and management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ajo.12521","type":"journal-article","created":{"date-parts":[[2016,9,5]],"date-time":"2016-09-05T06:02:42Z","timestamp":1473055362000},"page":"308-314","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["Impact of type 2 diabetes, obesity and glycaemic control on pregnancy outcomes"],"prefix":"10.1111","volume":"57","author":[{"given":"Sally K.","family":"Abell","sequence":"first","affiliation":[{"name":"Monash Centre for Health Research and Implementation School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia"},{"name":"Diabetes and Vascular Medicine Unit Monash Health Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline A.","family":"Boyle","sequence":"additional","affiliation":[{"name":"Refugee and Indigenous Women's Health Monash Centre for Health Research and Implementation School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia"},{"name":"Monash Women's Services Monash Health Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbora","family":"de Courten","sequence":"additional","affiliation":[{"name":"Diabetes and Vascular Medicine Unit Monash Health Melbourne Victoria Australia"},{"name":"Chronic Disease Prevention Monash Centre for Health Research and Implementation School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgia","family":"Soldatos","sequence":"additional","affiliation":[{"name":"Monash Centre for Health Research and Implementation School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia"},{"name":"Diabetes and Vascular Medicine Unit Monash Health Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Euan M.","family":"Wallace","sequence":"additional","affiliation":[{"name":"Monash Women's Maternity Services Monash Health Melbourne Victoria Australia"},{"name":"Department of Obstetrics and Gynaecology Ritchie Centre Monash University Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia","family":"Zoungas","sequence":"additional","affiliation":[{"name":"Diabetes and Vascular Medicine Unit Monash Health Melbourne Victoria Australia"},{"name":"Diabetes, Vascular Health and Ageing Monash Centre for Health Research and Implementation School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena J.","family":"Teede","sequence":"additional","affiliation":[{"name":"Monash Centre for Health Research and Implementation School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia"},{"name":"Diabetes and Vascular Medicine Unit Monash Health Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,9,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.2174\/157339909788920893"},{"key":"e_1_2_8_3_1","unstructured":"National Institute for Health and Care Excellence.Diabetes in pregnancy: management of diabetes and its complications from preconception to the postnatal period. Published 25 February 2015. [Retrieved September 16 2015.] Available fromhttp:\/\/nice.org.uk\/guidance\/ng3."},{"key":"e_1_2_8_4_1","unstructured":"Australian Institute of Health and Welfare 2010.Diabetes in pregnancy: its impact on Australian women and their babies. Diabetes series no. 14. Cat. no. CVD 52.Canberra:AIHW. 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WHO Technical Report Series 894.Geneva:World Health Organization 2000."},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja11.11331"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2014.08.005"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20172"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/254901"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc13-1934"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2011.587059"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2393-6-30"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016340903176859"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2013.10.004"}],"container-title":["Australian and New Zealand Journal of Obstetrics and Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajo.12521","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajo.12521","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajo.12521","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T03:39:19Z","timestamp":1695526759000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/ajo.12521"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,5]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["10.1111\/ajo.12521"],"URL":"https:\/\/doi.org\/10.1111\/ajo.12521","archive":["Portico"],"relation":{},"ISSN":["0004-8666","1479-828X"],"issn-type":[{"value":"0004-8666","type":"print"},{"value":"1479-828X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,5]]},"assertion":[{"value":"2016-05-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-07-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-09-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}