{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T05:41:58Z","timestamp":1788327718989,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,7,10]],"date-time":"2017-07-10T00:00:00Z","timestamp":1499644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001238","name":"Society of Hospital Pharmacists of Australia","doi-asserted-by":"publisher","award":["SAQ1406"],"award-info":[{"award-number":["SAQ1406"]}],"id":[{"id":"10.13039\/501100001238","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1070421"],"award-info":[{"award-number":["1070421"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1073514"],"award-info":[{"award-number":["1073514"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1082548"],"award-info":[{"award-number":["1082548"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2017,12]]},"abstract":"\n Aim<\/jats:title>\n \n To investigate trends in receipt and timing of antenatal corticosteroid (\n ACS<\/jats:styled-content>\n ) administration over a ten\u2010year interval.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Retrospective cohort study of all live births from 2006 to 2015 occurring at a tertiary level teaching hospital in Adelaide, Australia. We analysed temporal trends in the receipt of single courses and repeat doses of\n ACS<\/jats:styled-content>\n s, according to administration timing prior to birth. The main outcome measures were receipt of a single course of\n ACS<\/jats:styled-content>\n and whether administration was \u2018Optimal\u2019 (\u226524\u00a0h to <seven days) or \u2018Suboptimal\u2019 (<24\u00a0h\n OR<\/jats:styled-content>\n \u22657\u00a0days) according to timing prior to birth, as well as administration of repeat doses.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Among 47\u00a0105 live births, 4191 (8.9%) received any\n ACS<\/jats:styled-content>\n , while 1009 (2.1%) received at least one repeat dose. From 2006\/7 to 2014\/15, receipt of a single course (\n relative risk (RR)<\/jats:styled-content>\n 1.33; 95%\n CI<\/jats:styled-content>\n 1.21, 1.47) or repeat dose of\n ACS<\/jats:styled-content>\n (\n RR<\/jats:styled-content>\n 1.24; 95%\n CI<\/jats:styled-content>\n 1.01, 1.55) increased. Among women giving birth between 23\u201334\u00a0weeks gestation, receipt of any\n ACS<\/jats:styled-content>\n increased from 75 to 84%, while an optimally timed single course of\n ACS<\/jats:styled-content>\n increased from 20.4 to 31.0% (\n RR<\/jats:styled-content>\n 1.40; 95%\n CI<\/jats:styled-content>\n 1.24, 1.87). From 2006\/7 to 2014\/15, the greatest increase in\n ACS<\/jats:styled-content>\n administration was evident among infants born 35\u201336 and \u226537\u00a0weeks gestation by caesarean section (\n RR<\/jats:styled-content>\n 1.94; 95%\n CI<\/jats:styled-content>\n 1.48, 2.55 and\n RR<\/jats:styled-content>\n 2.55; 95%\n CI<\/jats:styled-content>\n 1.86, 3.50, respectively).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n While frequently used, less than half of\n ACS<\/jats:styled-content>\n administration prior to preterm birth was optimally timed. The impact of suboptimal\n ACS<\/jats:styled-content>\n timing on neonatal outcomes requires further investigation.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ajo.12657","type":"journal-article","created":{"date-parts":[[2017,7,10]],"date-time":"2017-07-10T06:02:40Z","timestamp":1499666560000},"page":"643-650","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Trends in receipt of single and repeat courses of antenatal corticosteroid administration among preterm and term births: A retrospective cohort study"],"prefix":"10.1111","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8554-4696","authenticated-orcid":false,"given":"Luke E.","family":"Grzeskowiak","sequence":"first","affiliation":[{"name":"SA Pharmacy Flinders Medical Centre SA Health Australia"},{"name":"Adelaide Medical School The Robinson Research Institute The University of Adelaide Adelaide Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosalie M.","family":"Grivell","sequence":"additional","affiliation":[{"name":"Adelaide Medical School The Robinson Research Institute The University of Adelaide Adelaide Australia"},{"name":"Department of Obstetrics and Gynaecology Flinders Medical Centre Bedford Park Australia"},{"name":"School of Medicine Flinders University Bedford Park Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben W.","family":"Mol","sequence":"additional","affiliation":[{"name":"Adelaide Medical School The Robinson Research Institute The University of Adelaide Adelaide Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,7,10]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.50.4.515"},{"key":"e_1_2_8_3_1","first-page":"CD004454","article-title":"Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth (Review)","volume":"19","author":"Roberts D","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"issue":"49","key":"e_1_2_8_4_1","first-page":"e41","article-title":"Relationship between the time interval from antenatal corticosteroid administration until preterm birth and the occurrence of respiratory morbidity","volume":"205","author":"Wilms FF","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)31081-7"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0004-8666.2003.00052.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2013.860523"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02590.x"},{"key":"e_1_2_8_9_1","volume-title":"Antenatal Corticosteroids Given to Women Prior to Birth to Improve Fetal, Infant, Child And Adult Health: Clinical Practice Guidelines","author":"Antenatal Corticosteroid Clinical Practice Guidelines Panel","year":"2015"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.13730"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000629"},{"key":"e_1_2_8_12_1","first-page":"CD003935","article-title":"Repeat doses of prenatal corticosteroids for women at risk of preterm birth for improving neonatal health outcomes","volume":"7","author":"Crowther CA","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1516783"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38547.416493.06"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/JCP.0b013e31826686bc"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.13612"},{"key":"e_1_2_8_17_1","volume-title":"Validation of the 1994 South Australian perinatal data collection form","author":"McLean A","year":"2001"},{"issue":"606","key":"e_1_2_8_18_1","first-page":"e601","article-title":"Promoting antenatal steroid use for fetal maturation: results from the California Perinatal Quality Care Collaborative","volume":"148","author":"Wirtschafter DD","year":"2006","journal-title":"J Pediatr"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31820c3c9b"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)35383-X"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.08.018"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.09.024"},{"key":"e_1_2_8_23_1","unstructured":"RobertsD.Antenatal Corticosteroids to Reduce Neonatal Morbidity and Mortality. 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