{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T06:26:40Z","timestamp":1781850400747,"version":"3.54.5"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,9,13]],"date-time":"2017-09-13T00:00:00Z","timestamp":1505260800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Rates of pre\u2010gestational obesity and gestational diabetes mellitus (<jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content>) are increasing in Australia. While both are established risk factors for neonatal hypoglycaemia, the additive effect of both risks on neonatal hypoglycaemia is not well understood.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To determine the influence of obesity on neonatal hypoglycaemia among infants born to <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> mothers. The authors hypothesise the presence of a greater frequency and severity of neonatal hypoglycaemia in infants born to obese <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>A cohort of 471 singleton <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> pregnancies was retrospectively studied. Women were divided into obese (body mass index (<jats:styled-content style=\"fixed-case\">BMI)<\/jats:styled-content>\u00a0\u2265\u00a030\u00a0kg\/m<jats:sup>2<\/jats:sup>) and not\u2010obese (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>\u00a0&lt;\u00a030\u00a0kg\/m<jats:sup>2<\/jats:sup>) groups according to self\u2010reported pre\u2010pregnancy weight. Perinatal outcomes and details of hypoglycaemic episodes were obtained by reviewing medical records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010five percent (104\/410) of the <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> mothers were obese, while 36% (146\/410) exceeded pregnancy weight gain recommendations. <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> and obesity resulted in a greater frequency of neonatal hypoglycaemia as compared to women with <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> alone (obese 44%, not obese 34%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.046). Obesity increased the likelihood of having multiple hypoglycaemic episodes (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.022). Excess weight gain increased the likelihood of the neonate requiring intravenous dextrose (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.0012). No differences were found in the likelihood of nursery admissions or lowest plasma glucose levels.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Pre\u2010pregnancy obesity and weight gain during pregnancy above the recommended limits increased the likelihood of neonatal hypoglycaemia among infants of <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> mothers. Further studies with larger cohorts are warranted to confirm our findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajo.12717","type":"journal-article","created":{"date-parts":[[2017,9,13]],"date-time":"2017-09-13T11:31:57Z","timestamp":1505302317000},"page":"291-297","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Effect of obesity on neonatal hypoglycaemia in mothers with gestational diabetes: A comparative study"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6295-3961","authenticated-orcid":false,"given":"Katherine","family":"Collins","sequence":"first","affiliation":[{"name":"Fiona Stanley Hospital  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raoul","family":"Oehmen","sequence":"additional","affiliation":[{"name":"School of Medicine University of Notre Dame Australia  Fremantle Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shailender","family":"Mehta","sequence":"additional","affiliation":[{"name":"School of Medicine University of Notre Dame Australia  Fremantle Western Australia Australia"},{"name":"Department of Neonatology Fiona Stanley Hospital  Perth Western Australia Australia"},{"name":"Telethon Kids Institute  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,13]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-010667"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2011.tb03001.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-011-2150-4"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6823-14-47"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-1790"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2006.tb00115.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP-10-0088"},{"key":"e_1_2_5_9_1","first-page":"685","article-title":"Diabetes and pregnancy; blood sugar of newborn infants during fasting and glucose administration","volume":"114","author":"Pedersen J","year":"1952","journal-title":"Ugeskr Laeger"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2010.521871"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-0719"},{"key":"e_1_2_5_12_1","first-page":"1","article-title":"Obesity: preventing and managing the global epidemic. 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