{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T21:45:50Z","timestamp":1755035150857,"version":"3.40.5"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,9,15]],"date-time":"2020-09-15T00:00:00Z","timestamp":1600128000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Australian Cervical Screening Program guidelines no longer recommend colposcopy and cytology at six\u00a0months following treatment of cervical intraepithelial neoplasia (CIN2\/3) and a co\u2010test of cure can be performed at 12\u00a0months without colposcopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To determine the usefulness of six\u2010month colposcopy and cytology and routine colposcopy with co\u2010testing at 12\u00a0months in detecting persistent or recurrent disease in patients treated for CIN2\/3.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We conducted a review of all patients with histologically proven CIN2\/3 who underwent a cervical excisional procedure between March 2012 and March 2017 in one specialised centre.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We examined 1215 cases and 750 remained after exclusions for analysis. At six months (722 cases, 96.2%) seven of 42 (16.7%) patients with high\u2010grade cytology had a high\u2010grade colposcopy and 24 of 42 (57.1%) had a normal colposcopy. Persistent CIN2\/3 was diagnosed in 12 cases (1.7%) and only 1\/3 had a high\u2010grade colposcopy. Cytology was more useful than colposcopy in detecting persistent disease. At 12 months (638 cases, 85%) routine colposcopy at the time of co\u2010testing had a high false positive rate with all high\u2010grade changes negative on biopsy and co\u2010test. Recurrent CIN2\/3 was diagnosed in five cases, and four had normal colposcopy at co\u2010testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There may be a delay in detection of persistent\/recurrent CIN2\/3 in a small number of cases without six\u2010month colposcopy and cytology; however, it is not likely to negatively impact overall clinical outcome. Co\u2010testing at 12\u00a0months following treatment of CIN2\/3 without colposcopy is safe and routine colposcopy at collection of the co\u2010test can be omitted.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajo.13248","type":"journal-article","created":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T16:05:37Z","timestamp":1601049937000},"page":"959-964","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Follow\u2010up after treatment of high\u2010grade cervical dysplasia: The utility of six\u2010month colposcopy and cytology and routine 12\u2010month colposcopy"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8586-2392","authenticated-orcid":false,"given":"Rhett","family":"Morton","sequence":"first","affiliation":[{"name":"Gynaecological Oncology Chris O\u2019Brien Lifehouse Sydney New South Wales 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