{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T22:31:32Z","timestamp":1790807492255,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,11,12]],"date-time":"2020-11-12T00:00:00Z","timestamp":1605139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Little is known about the pregnancy outcomes of women who have had a stroke prior to a first pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To identify a cohort of primiparous women giving birth to a single baby and compare the pregnancy outcomes of those with a pre\u2010pregnancy stroke hospitalisation record to those without a stroke hospitalisation record.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Record linkage study of all primiparous women aged 15\u201344\u00a0years with singleton pregnancies birthing in New South Wales, Australia from 2003 to 2015. Stroke was identified from 2001 to 2015 hospital data using International Classification of Diseases tenth Edition \u2013 Australian Modification codes I60\u201364. Women whose first hospital record of stroke was during pregnancy or &lt;42\u00a0days after birth were excluded. Outcomes included diabetes or hypertension during pregnancy, mode of delivery, haemorrhage, severe maternal morbidity (validated composite outcome indicator), gestational age at birth, Apgar score (1\u00a0min\u00a0&lt;\u00a07), and small\u2010for\u2010gestational age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 487\u00a0767 women with a first pregnancy, 124 (2.5\/10\u00a0000) had a hospital record which included a pre\u2010pregnancy stroke diagnosis. Women with a stroke history were more likely to have an early\u2010term delivery (37\u201338\u00a0weeks; relative risk (RR) 1.49, 95% CI 1.17\u20131.90) and a pre\u2010labour caesarean (RR 2.83, 95% CI 2.20\u20133.63). There were no significant differences in other maternal or neonatal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This is the largest reported study of pregnancy and birth outcomes for women with a history of stroke. 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