{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T04:36:57Z","timestamp":1771475817410,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T00:00:00Z","timestamp":1632700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>A variety of surgical techniques are available for vaginal prolapse repair, indicating a lack of consensus. A debate regarding the utility of hydrodissection for splitting the surgical plane of the vaginal wall exists. The aim of this study is to evaluate the impact of hydrodissection in anterior colporrhaphy (AC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials<\/jats:title><jats:p>Patients undergoing primary AC were randomly assigned to an approach with (study group) versus without (control group) hydrodissection. Five surgeons performed both techniques, and the trimmed vaginal tissue was retrieved for histological analysis. Two pathologists, blinded to the surgical approach, evaluated the presence of a loose connective tissue at the surgical dissection plane (controversially deemed \u2018fascia\u2019, as explained in this article). In addition, we compared the operative time, pain score and haemoglobin levels. After statistical analysis, data were presented using percentile, and statistical significance was tested using the \u03c7<jats:sup>2<\/jats:sup> and Fisher\u2019s exact tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010six patients underwent primary elective AC, with 23 patients in each, the study and control groups. The groups were comparable regarding age (study group 60.33 \u00b1 11.95 years and control group 59.86 \u00b1 12.04, <jats:italic>P<\/jats:italic> = 0.90), menopausal status (study group 17 (73.9%) and control group 15 (68.2%), <jats:italic>P<\/jats:italic> = 0.67) and other characteristics. We found no difference in sample characteristics between the two groups. Connective tissue was found in only 13.6% (<jats:italic>n<\/jats:italic> = 3) of patients after hydrodissection and in 27.3% (<jats:italic>n<\/jats:italic> = 6) of patients without hydrodissection (<jats:italic>P<\/jats:italic> = 0.46). The hydrodissection group had significantly less bleeding than the control group (\u0394HB 0.66 \u00b1 0.66 vs 1.21 \u00b1 0.84, <jats:italic>P<\/jats:italic> = 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>After hydrodissection, less bleeding was noted without compromise the surgical planes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajo.13431","type":"journal-article","created":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T06:14:00Z","timestamp":1632809640000},"page":"98-103","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The role of hydrodissection in native tissue repair of anterior vaginal wall defects"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2769-8651","authenticated-orcid":false,"given":"Polina","family":"Schwarzman","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Soroka University Medical Center Ben\u2010Gurion University of the Negev Beer\u2010Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0202-9486","authenticated-orcid":false,"given":"Benzion","family":"Samueli","sequence":"additional","affiliation":[{"name":"Department of Pathology Soroka University Medical Center Ben\u2010Gurion University of the Negev Beer\u2010Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Shaco\u2010Levy","sequence":"additional","affiliation":[{"name":"Department of Pathology Soroka University Medical Center Ben\u2010Gurion University of the Negev Beer\u2010Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yael","family":"Baumfeld","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Soroka University Medical Center Ben\u2010Gurion University of the Negev Beer\u2010Sheva Israel"},{"name":"Faculty of Health Sciences Clinical Research Center Soroka University Medical Center Ben\u2010Gurion University of the Negev Beer\u2010Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elad","family":"Leron","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Soroka University Medical Center Ben\u2010Gurion University of the Negev Beer\u2010Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adi Y.","family":"Weintraub","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Soroka University Medical Center Ben\u2010Gurion University of the Negev Beer\u2010Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,27]]},"reference":[{"issue":"1","key":"e_1_2_6_2_1","first-page":"120","article-title":"Anterior needle\u2010guided mesh in advanced pelvic organ prolapse: Apical fixation on sacrospinous ligaments","volume":"172","author":"Neuman M","year":"2014","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-013-2172-1"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012079"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-016-3032-6"},{"key":"e_1_2_6_6_1","unstructured":"Food and Drug Administration.Urogynecologic surgical mesh: Update on the safety and effectiveness of transvaginal placement for pelvic organ prolapse. FDA Saf Commun [Internet]2011; (July):1\u201315. [Accessed 14 September 2021.] Available from URL:https:\/\/www.fda.gov\/media\/81123\/download"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31823ed1d9"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-012-1677-3"},{"key":"e_1_2_6_9_1","unstructured":"U.S. Food and Drug Administration.FDA takes action to protect women\u2019s health orders manufacturers of surgical mesh intended for transvaginal repair of pelvic organ prolapse to stop selling all devices. 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