{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T01:27:37Z","timestamp":1785461257703,"version":"3.56.0"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,10,8]],"date-time":"2021-10-08T00:00:00Z","timestamp":1633651200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001774","name":"University of Sydney","doi-asserted-by":"publisher","award":["197589"],"award-info":[{"award-number":["197589"]}],"id":[{"id":"10.13039\/501100001774","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Active surveillance for cervical intraepithelial neoplasia 2 (CIN2) would allow time for most cases to regress naturally and in turn avoid potentially unnecessary and harmful treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine reasons for choosing active surveillance over surgery among women given a hypothetical diagnosis of CIN2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Women residing in Australia aged 25\u201340\u00a0years with no prior diagnosis of cervical cancer, cervical abnormality CIN2 or above, and\/or previous hysterectomy, were randomised to one of four identical hypothetical scenarios of testing human papillomavirus (HPV)\u2010positive: high\u2010grade cytology and a diagnosis of CIN2 that used alternate terminology to describe resolution of abnormal cells and\/or inclusion of an overtreatment statement. Participants selected active surveillance or surgery after viewing the scenario and free\u2010text reason\/s for their choice were thematically analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 1638 women randomised, 79% (<jats:italic>n<\/jats:italic>\u00a0=\u00a01293) opted for active surveillance. The most common reasons for choosing active surveillance included concerns about surgery and associated risks, preferring to \u2018wait and see\u2019, trusting the doctor\u2019s recommendations and having an emotional response toward surgery. For women who chose surgery, being risk\u2010averse, addressing the issue straight away and perceiving surgery to be the better option for them were the most common themes identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>When presented with balanced information on the benefits and harms of different management options for CIN2 and given a choice, most women in this hypothetical situation chose active surveillance over surgery. Addressing women\u2019s concerns about active surveillance may open up the possibility that if deemed safe, it could be an acceptable alternative for women.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajo.13440","type":"journal-article","created":{"date-parts":[[2021,10,10]],"date-time":"2021-10-10T14:17:09Z","timestamp":1633875429000},"page":"125-132","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Understanding women\u2019s choices for management of cervical intraepithelial neoplasia 2 (CIN2): Qualitative analysis of a randomised experimental study"],"prefix":"10.1111","volume":"62","author":[{"given":"Gemma","family":"Keers","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Health School of Public Health The University of Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kozue","family":"Yamada","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health School of Public Health The University of Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Pickles","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health School of Public Health The University of Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katy","family":"Bell","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health School of Public Health The University of Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0030-2431","authenticated-orcid":false,"given":"Kirsten","family":"Black","sequence":"additional","affiliation":[{"name":"Discipline of Obstetrics, Gynaecology and Neonatology Faculty of Medicine and Health Central Clinical School The University of Sydney Sydney New South Wales Australia"},{"name":"Royal Prince Alfred Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1035-7110","authenticated-orcid":false,"given":"Deborah","family":"Bateson","sequence":"additional","affiliation":[{"name":"Discipline of Obstetrics, Gynaecology and Neonatology Faculty of Medicine and Health Central Clinical School The University of Sydney Sydney New South Wales Australia"},{"name":"Family Planning New South Wales Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8080-6359","authenticated-orcid":false,"given":"Rachael H.","family":"Dodd","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health School of Public Health The University of Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,8]]},"reference":[{"key":"#cr-split#-e_1_2_8_2_1.1","unstructured":"Department of Health.National Cervical Screening Program Policies[Internet] Canberra [updated 2020 September 06"},{"key":"#cr-split#-e_1_2_8_2_1.2","unstructured":"cited 2020 September 6]. 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