{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T19:13:38Z","timestamp":1784229218226,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,6,14]],"date-time":"2022-06-14T00:00:00Z","timestamp":1655164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Pulmonary arterial hypertension (PAH) is a high\u2010risk condition during pregnancy, with recent literature describing mortality rates of up to 23%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To describe the course and outcomes of pregnancy for women with PAH in a major Australian metropolitan referral centre over a 15\u2010year period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective review of medical records of all pregnant women with PAH over the period 2005\u20132020.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We report the outcomes of nine pregnancies in six women. In five women, seven pregnancies proceeded to term with birth of a healthy neonate, five vaginal births and two caesareans. Two women opted for a termination of pregnancy in the first trimester following counselling. The planning of care and patient\u2010centred decision\u2010making was individually tailored by a multidisciplinary team. The pulmonary hypertension clinic provided specialist support including the management of pulmonary vasodilators. All women who delivered a live offspring received neuraxial anaesthesia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Women with this condition are ideally managed in a centre with expertise in PAH; counselling regarding the risks is imperative. Regional anaesthesia, irrespective of the mode of delivery, facilitated safe delivery and improved patient experience. The option of aiming for a term vaginal birth needs to be considered in these complex women.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajo.13557","type":"journal-article","created":{"date-parts":[[2022,6,14]],"date-time":"2022-06-14T11:40:29Z","timestamp":1655206829000},"page":"66-73","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A case series describing the multidisciplinary management of pulmonary arterial hypertension in pregnancy: Time for optimism"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1670-3563","authenticated-orcid":false,"given":"Samuel","family":"Boyers","sequence":"first","affiliation":[{"name":"Department of Anaesthesia &amp; Perioperative Medicine Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0306-4160","authenticated-orcid":false,"given":"Roshini","family":"Nayyar","sequence":"additional","affiliation":[{"name":"Westmead Institute for Maternal and Fetal Medicine, Women's and Newborn Health Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7569-1016","authenticated-orcid":false,"given":"Sarah J.","family":"Melov","sequence":"additional","affiliation":[{"name":"Westmead Institute for Maternal and Fetal Medicine, Women's and Newborn Health Westmead Hospital  Sydney New South Wales Australia"},{"name":"Faculty of Medicine and Health, Reproduction and Perinatal Centre University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Tanous","sequence":"additional","affiliation":[{"name":"Department of Cardiology Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2176-933X","authenticated-orcid":false,"given":"Jane","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia &amp; Perioperative Medicine Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,14]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"903","article-title":"2015 ESC\/ERS guidelines for the diagnosis and treatment of pulmonary hypertension. The joint task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS)endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC)","volume":"46","author":"Gali\u00e8 N","year":"2015","journal-title":"Int Soc Heart Lung Transplant"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01913\u20102018"},{"key":"e_1_2_6_4_1","unstructured":"Australian Government Department of Health PBS (Pharmaceutical Benefits Scheme) Drug Utilisation Sub\u2010committee.Pulmonary Arterial Hypertension (PAH) Medicines Utilisation Analysis.Aust GovtFeb 2015. 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