{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:53:17Z","timestamp":1790268797759,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T00:00:00Z","timestamp":1658880000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The benefit of antenatal corticosteroid (ACS) administration for the prevention of neonatal morbidity and mortality has been well described for preterm infants. Some studies have demonstrated a benefit for infants born by elective caesarean section (CS) at late preterm or term gestations. However, the neonatal benefits of ACS are not well described when given to pregnant women with diabetes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The aim of this study was to evaluate the neonatal outcomes following ACS administration in women with pre\u2010gestational diabetes mellitus (PGDM) when administered prior to elective CS after 36\u2009weeks gestation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective observational study included all women with PGDM who gave birth by elective CS between 36<jats:sup>+0<\/jats:sup> and 38<jats:sup>+6<\/jats:sup> weeks gestation. Neonatal outcomes for exposed participants were compared to outcomes for non\u2010exposed participants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 306 women identified, 65 (21.2%) were exposed to ACS within seven\u00a0days prior to birth and 241 (78.8%) were not. Although not statistically significant, ACS\u2010exposed infants born prior to 38<jats:sup>+0<\/jats:sup> weeks were less likely to require respiratory support or neonatal nursery admission compared to those who were not exposed; however, exposed infants born after 37<jats:sup>+0<\/jats:sup> weeks were more likely to require parenteral treatment for neonatal hypoglycaemia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study did not demonstrate any statistically significant beneficial or harmful effects of ACS in neonates of women with PGDM who are born by elective CS. While it is plausible that ACS could reduce neonatal respiratory morbidity in this population, further prospective studies evaluating the benefits and harms are required before recommending this practice.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajo.13586","type":"journal-article","created":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T10:40:19Z","timestamp":1658918419000},"page":"93-98","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Neonatal outcomes following antenatal corticosteroid administration prior to elective caesarean delivery in women with pre\u2010gestational diabetes: A retrospective cohort study"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2632-353X","authenticated-orcid":false,"given":"Iniyaval","family":"Thevathasan","sequence":"first","affiliation":[{"name":"Department of Maternal Fetal Medicine The Royal Women's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amalia","family":"Karahalios","sequence":"additional","affiliation":[{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Unterscheider","sequence":"additional","affiliation":[{"name":"Department of Maternal Fetal Medicine The Royal Women's Hospital  Melbourne Victoria Australia"},{"name":"Department of Obstetrics and Gynaecology The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Leung","sequence":"additional","affiliation":[{"name":"Pharmacy The Royal Women's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Walker","sequence":"additional","affiliation":[{"name":"Women's and Children's Services, Sunshine Hospital Western Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6263-0030","authenticated-orcid":false,"given":"Joanne M.","family":"Said","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology The University of Melbourne  Melbourne Victoria Australia"},{"name":"Department of Maternal Fetal Medicine, Joan Kirner Women's and Children's at Sunshine Hospital Western Health St Albans  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,27]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"Cd004454","article-title":"Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth","volume":"3","author":"Robersts D","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38547.416493.06"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2016.01.026"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2014.958461"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12447"},{"key":"e_1_2_5_7_1","unstructured":"Australian Institute of Health and Welfare (AIWH).Australia's Mothers and Babies 2014 \u2013 in Brief. 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