{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T07:22:48Z","timestamp":1792135368765,"version":"4.4.0"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T00:00:00Z","timestamp":1704672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pregnancy in kidney transplant recipients has become increasingly common. However, pregnancy carries higher risks to these patients compared to the general population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To describe pregnancy outcomes in kidney transplant recipients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We conducted a single\u2010centre retrospective cohort study of kidney transplant recipients who delivered after 20\u2009weeks gestation at a quaternary hospital in Victoria, Australia, between 2000 and 2022 inclusive.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study included 37 pregnancies from 27 patients, accounting for 38 infants. Over half of recorded pregnancies occurred in the past five\u2009years (56.8%, <jats:italic>n<\/jats:italic>\u2009=\u200921). There were high rates of pre\u2010existing hypertension (75.7%, <jats:italic>n<\/jats:italic>\u2009=\u200928). Pregnancy\u2010induced hypertension and pre\u2010eclampsia were common antenatal complications (21.6%, <jats:italic>n<\/jats:italic>\u2009=\u20098 and 48.6%, <jats:italic>n<\/jats:italic>\u2009=\u200918 respectively). Soluble fms\u2010like tyrosine kinase\u20101 \/ placental growth factor ratios were elevated in all patients who developed severe pre\u2010eclampsia (16.2%, <jats:italic>n<\/jats:italic>\u2009=\u20096). The median gestational age at birth was 36.4\u2009weeks (range 20\u201340.4, Q<jats:sub>1<\/jats:sub> 32.9, Q<jats:sub>3<\/jats:sub> 37.6) and 59.5% (<jats:italic>n<\/jats:italic>\u2009=\u200922) of births were preterm. Unplanned caesarean without labour was the most common mode of birth (35.1%, <jats:italic>n<\/jats:italic>\u2009=\u200913). The overall caesarean rate was 62.1% (<jats:italic>n<\/jats:italic>\u2009=\u200923). Post\u2010partum haemorrhage complicated over half of pregnancies (56.8%, <jats:italic>n<\/jats:italic>\u2009=\u200921). Fifty percent (<jats:italic>n<\/jats:italic>\u2009=\u200919) of infants were admitted for neonatal care, in particular neonatal intensive care, and had low birthweights under 2500\u2009g. While there was a transient deterioration in kidney function, there was no graft rejection within one\u2009year of birth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Clinicians should consider the high rates of pre\u2010existing hypertension, preterm birth, and caesarean birth when counselling and managing pregnant kidney transplant recipients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajo.13786","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T10:34:08Z","timestamp":1704710048000},"page":"269-276","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Pregnancy outcomes post\u2010kidney transplantation across 23\u2009years"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5823-9079","authenticated-orcid":false,"given":"Jessica","family":"Han","sequence":"first","affiliation":[{"name":"Melbourne Medical School University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2142-1678","authenticated-orcid":false,"given":"Ciara Anne","family":"McCormick","sequence":"additional","affiliation":[{"name":"Department of Maternal Fetal Medicine Royal Women's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Krelle","sequence":"additional","affiliation":[{"name":"Department of Nephrology Royal Melbourne Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9194-6339","authenticated-orcid":false,"given":"Paul","family":"Champion de Crespigny","sequence":"additional","affiliation":[{"name":"Melbourne Medical School University of Melbourne  Melbourne Victoria Australia"},{"name":"Department of Nephrology Royal Melbourne Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Unterscheider","sequence":"additional","affiliation":[{"name":"Department of Maternal Fetal Medicine Royal Women's Hospital  Melbourne Victoria Australia"},{"name":"Department of Obstetrics and Gynaecology The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2020.06.004"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2011.03656.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/4539342"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-019-1213-5"},{"key":"e_1_2_7_6_1","unstructured":"Registry A.24th report Appendix I.2001. Adelaide Australia: Australia and New Zealand Dialysis and Transplant Registry."},{"key":"e_1_2_7_7_1","unstructured":"Registry A.45th report Chapter\u00a02: Prevalence of kidney failure with replacement therapy.2022. Adelaide Australia: Australia and New Zealand Dialysis and Transplant Registry."},{"key":"e_1_2_7_8_1","unstructured":"Registry A.45th report Chapter\u00a06: Kidney transplantation.2022. Adelaide Australia. Australia and New Zealand Dialysis and Transplant Registry."},{"key":"e_1_2_7_9_1","unstructured":"Registry AaNZOD.Organ Waiting List 2023. [Accessed 16 August 2023.] Available from URL:https:\/\/www.anzdata.org.au\/anzod\/publications\u20102\/organ\u2010waiting\u2010list\/"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2008121241"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12452"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2022.03.015"},{"key":"e_1_2_7_13_1","unstructured":"NankervisAJ HdM MosesRGet al.ADIPS consensus guidelines for the testing and diagnosis of hyperglycaemia in pregnancy in Australia and New Zealand.2014."},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2018.05.004"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12399"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(85)90298-4"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.13479"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.13089"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2018.12.003"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2015.08.023"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002404"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2022.09.034"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.27378"},{"key":"e_1_2_7_24_1","unstructured":"World Health Organization.WHO Statement on Caesarean Section Rates.2015. 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