{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T09:50:42Z","timestamp":1768902642025,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T00:00:00Z","timestamp":1715212800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Unconfirmed beta\u2010lactam allergy in pregnant people has been associated with higher morbidity, unnecessary exposure to broad\u2010spectrum antibiotics and prolonged hospitalisation. There are no published data on beta\u2010lactam allergies in pregnant people in Australia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The aim was to describe patient\u2010reported beta\u2010lactam allergies and appropriateness for antibiotic allergy de\u2010labelling in a maternity cohort in Australia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Maternity patients aged \u226518\u2009years admitted to our institution between March 2021 and June 2021 with a beta\u2010lactam allergy documented in their electronic medical record were interviewed for details of their allergy. The documented allergies were compared to the allergy history obtained from the interview. Severity of the allergy was rated, and appropriateness for allergy de\u2010labelling was assessed using the Victorian Therapeutics Advisory Group beta\u2010lactam antibiotic allergy assessment tool.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and fifty\u2010three beta\u2010lactam allergies (182 reactions) were reported by 145 patients. Penicillin class antibiotics were the most frequently implicated, including unspecified penicillins (95\/153, 62%), amoxicillin (19\/153, 13%) and amoxicillin\u2010clavulanate (8\/153, 5%). Allergy documentation required amending in 52 of 145 patients (36%); 85 of 153 (56%) of the beta\u2010lactam allergies were considered low risk and potentially appropriate for direct oral re\u2010challenge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Beta\u2010lactam allergies were inaccurately documented in more than one third of the maternity patients included in our study. As such, education of maternity care providers about the importance of accurate allergy history taking remains an urgent unmet need. Furthermore, allergy assessment and de\u2010labelling during pregnancy should be considered in maternity patients to optimise antibiotic prescribing and to improve maternal and neonatal health outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajo.13819","type":"journal-article","created":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T09:30:50Z","timestamp":1715247050000},"page":"489-493","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Beta\u2010lactam allergy risk stratification in a maternity population in Australia: Scope for allergy de\u2010labelling"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-7320-2964","authenticated-orcid":false,"given":"Wirawan","family":"Jeong","sequence":"first","affiliation":[{"name":"Pharmacy Department The Royal Women's Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahad","family":"Saleh","sequence":"additional","affiliation":[{"name":"Pharmacy Department The Royal Women's Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon","family":"Heap","sequence":"additional","affiliation":[{"name":"Infection Prevention and Control The Royal Women\u2032s Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vi","family":"Pham","sequence":"additional","affiliation":[{"name":"Pharmacy Department The Royal Women's Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Leung","sequence":"additional","affiliation":[{"name":"Pharmacy Department The Royal Women's Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0727-8446","authenticated-orcid":false,"given":"Sushena","family":"Krishnaswamy","sequence":"additional","affiliation":[{"name":"Infection Prevention and Control The Royal Women\u2032s Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-014-0476-y"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.19283"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12881"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkw008"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(99)70439-2"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12390"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2018-026624"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0150514"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.7812\/TPP\/16-080"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/a\u20102096\u20105002"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa653"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000004213"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2020.08.012"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2022.100674"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2020.10.063"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2021.01.023"},{"key":"e_1_2_8_18_1","unstructured":"Victorian Therapeutics Advisory Group (VICTAG).VicTAG Antibiotic Allergy Assessment Tool.https:\/\/www.victag.org.au\/VicTAG_Antibiotic_Allergy_Assessment_Tool_Final_6_11_191_copy.pdf. Accessed 09\/03\/2023."},{"key":"e_1_2_8_19_1","volume-title":"Antimicrobial Stewardship Clinical Care Standard","author":"Australian Commission on Safety and Quality in Health Care","year":"2020"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajhp\/58.18.1722"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32218-9"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2022.03.025"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2023.101074"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003669"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix794"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1685503"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0179117"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.839079"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2018.07.048"}],"container-title":["Australian and New Zealand Journal of Obstetrics and Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajo.13819","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T11:12:01Z","timestamp":1734693121000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/ajo.13819"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,9]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1111\/ajo.13819"],"URL":"https:\/\/doi.org\/10.1111\/ajo.13819","archive":["Portico"],"relation":{},"ISSN":["0004-8666","1479-828X"],"issn-type":[{"value":"0004-8666","type":"print"},{"value":"1479-828X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,9]]},"assertion":[{"value":"2024-01-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}