{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T07:35:19Z","timestamp":1785569719573,"version":"3.56.0"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T00:00:00Z","timestamp":1747267200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T00:00:00Z","timestamp":1747267200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the interobserver agreement of the International Ovarian Tumour Analysis (IOTA) ultrasound\u2010based simple rules risk (SRRisk) score, the logistic regression model 2 (LR2), the Assessment of Different NEoplasias in the adneXa (ADNEX) model and the Ovarian\u2010Adnexal Reporting and Data System (O\u2010RADS) in an Australian, population\u2010based context.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective multi\u2010centre study was performed between January 2020 and January 2021. The study included 198 women with adnexal masses examined with transvaginal grey scale and power Doppler ultrasound. Participants were recruited from the multidisciplinary oncology meetings (MDT) of two tertiary cancer centres. Two independent radiologists described the adnexal masses according to the SRR, LR2 scores, ADNEX model, and O\u2010RADS. Values &gt;\u200930\u2009units different were considered differential and &gt;\u200950\u2009units were considered highly differential.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From 198 patients, 128 were diagnosed with benign ovarian masses, 53 with malignant and 17 patients with borderline tumours. There was strong agreement (Cohen's kappa 0.8) for intra\u2010tumour blood flow, number of cysts locules, and presence of blood flow within solid projections. Interobserver agreement was moderate (Cohen's kappa 0.60\u20130.79) for the presence of free pelvic fluid\/ascites, solid components, unilocular cysts and acoustic shadows. Of the 198 cases, 10 (5%) cases were highly differential and (38\/198) 19% were differential for SRRisk, (20\/198) 10% highly differential and (36\/198) 18% differential for LR2, and (10\/198) 5% and (24\/198) 12% for ADNEXA model, respectively. Comparison of O\u2010RADS scores between the two observers showed a moderate agreement with a kappa of 0.65. In 7\/198 (4%) cases, the difference between observers was for 2 or more categories when using the O\u2010RADS score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our results suggested that interobserver variation was present in evaluating adnexal masses using well established ultrasonographic diagnostic models. Implementation of sonographic ovarian cancer risk prediction models will need to consider this issue and ensure examiners have adequate training in the technique, and standard operating procedures are in place to reduce interobserver variability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ajo.70036","type":"journal-article","created":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T08:21:11Z","timestamp":1747297271000},"page":"792-799","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Subjective Assessment of Adnexal Masses Using Various Ultrasonographic Diagnostic Models: An Analysis of Interobserver Variability"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5078-127X","authenticated-orcid":false,"given":"Ivana","family":"Rizzuto","sequence":"first","affiliation":[{"name":"Department of Gynaecology Ipswich Hospital  Ipswich Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shohreh","family":"Rezai","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Royal Brisbane and Women's Hospital  Herston Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annah","family":"Lane","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Mater Hospital  South Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marita","family":"Prior","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Royal Brisbane and Women's Hospital  Herston Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristy P.","family":"Robledo","sequence":"additional","affiliation":[{"name":"NHMRC Clinical Trials Centre, University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Obermair","sequence":"additional","affiliation":[{"name":"Centre for Clinical Research, Faculty of Medicine, the University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(08)70005-6"},{"key":"e_1_2_6_3_1","first-page":"370","article-title":"Validation of Models to Diagnose Ovarian Cancer in Patients Managed Surgically or Conservatively: Multicentre Cohort Study","volume":"30","author":"Van Calster B.","year":"2020","journal-title":"BMJ"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0000000000000865"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2020.08.018"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(90)90401-6"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2003.09.009"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2000.00287.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.01.007"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.01.7632"},{"issue":"1","key":"e_1_2_6_11_1","first-page":"32","article-title":"Practical Guidance for Applying the ADNEX Model From the IOTA Group to Discriminate Between Different Subtypes of Adnexal Tumours","volume":"7","author":"Van Calster B.","year":"2015","journal-title":"Facts, Views & Vision in ObGyn"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2019191150"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2020.02.022"},{"key":"e_1_2_6_14_1","volume-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2022"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/096228029900800204"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/001316446002000104"},{"key":"e_1_2_6_17_1","volume-title":"Statistical Methods for Rates and Proportions","author":"Fleiss J. L.","year":"2013"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0960-7692.2001.00500.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-14-0906"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5365"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.24777"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.13254"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2013.04.003"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2016.227"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2022.5969"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.304.6840.1491"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2023.09.018"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2282011860"}],"container-title":["Australian and New Zealand Journal of Obstetrics and Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajo.70036","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ajo.70036","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajo.70036","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T14:56:29Z","timestamp":1768229789000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/ajo.70036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,15]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1111\/ajo.70036"],"URL":"https:\/\/doi.org\/10.1111\/ajo.70036","archive":["Portico"],"relation":{},"ISSN":["0004-8666","1479-828X"],"issn-type":[{"value":"0004-8666","type":"print"},{"value":"1479-828X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,15]]},"assertion":[{"value":"2024-08-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}